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Leukemia

Epigenetic Silencing of the Circadian Clock Gene CRY1 is Associated with an Indolent Clinical Course in Chronic Lymphocytic Leukemia

Maher Hanoun, Lewin Eisele, Masako Suzuki, John M. Greally, Andreas Hüttmann, Semra Aydin, René Scholtysik, Ludger Klein-Hitpass, Ulrich Dührsen, Jan Dürig

published 28 Mar 2012

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Aronia melanocarpa Juice Induces a Redox-Sensitive p73-Related Caspase 3-Dependent Apoptosis in Human Leukemia Cells

Tanveer Sharif, Mahmoud Alhosin, Cyril Auger, Carole Minker, Jong-Hun Kim, Nelly Etienne-Selloum, Pierre Bories, Hinrich Gronemeyer, Annelise Lobstein, Christian Bronner, Guy Fuhrmann, Valérie B. Schini-Kerth

published 08 Mar 2012

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Accurate Detection of Carcinoma Cells by Use of a Cell Microarray Chip

Shohei Yamamura, Shouki Yatsushiro, Yuka Yamaguchi, Kaori Abe, Yasuo Shinohara, Eiichi Tamiya, Yoshinobu Baba, Masatoshi Kataoka

published 01 Mar 2012

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Inhibition of the Intrinsic but Not the Extrinsic Apoptosis Pathway Accelerates and Drives Myc-Driven Tumorigenesis Towards Acute Myeloid Leukemia

Kari Högstrand, Eduar Hejll, Birgitta Sander, Björn Rozell, Lars-Gunnar Larsson, Alf Grandien

published 29 Feb 2012

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Transforming and Tumorigenic Activity of JAK2 by Fusion to BCR: Molecular Mechanisms of Action of a Novel BCR-JAK2 Tyrosine-Kinase

Álvaro Cuesta-Domínguez, Mara Ortega, Cristina Ormazábal, Matilde Santos-Roncero, Marta Galán-Díez, Juan Luis Steegmann, Ángela Figuera, Eva Arranz, José Luis Vizmanos, Juan A. Bueren, Paula Río, Elena Fernández-Ruiz

published 27 Feb 2012

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3, 3′-Diindolylmethane Exhibits Antileukemic Activity In Vitro and In Vivo through a Akt-Dependent Process

Ning Gao, Senping Cheng, Amit Budhraja, E-Hu Liu, Jieping Chen, Deying Chen, Zailin Yang, Jia Luo, Xianglin Shi, Zhuo Zhang

published 21 Feb 2012

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Contribution of an Aged Microenvironment to Aging-Associated Myeloproliferative Disease

Virag Vas, Corinna Wandhoff, Karin Dörr, Anja Niebel, Hartmut Geiger

published 21 Feb 2012

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Prolonged Exposure to a Mer Ligand in Leukemia: Gas6 Favors Expression of a Partial Mer Glycoform and Reveals a Novel Role for Mer in the Nucleus

Justine Migdall-Wilson, Christine Bates, Jennifer Schlegel, Luis Brandão, Rachel M. A. Linger, Deborah DeRyckere, Douglas K. Graham

published 20 Feb 2012

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Evolution of Resistance to Aurora Kinase B Inhibitors in Leukaemia Cells

Timothy W. Failes, Gorjana Mitic, Heba Abdel-Halim, Sela T. Po'uha, Marjorie Liu, David E. Hibbs, Maria Kavallaris

published 16 Feb 2012

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Optical Imaging of Disseminated Leukemia Models in Mice with Near-Infrared Probe Conjugated to a Monoclonal Antibody

Sabrina Pesnel, Arnaud Pillon, Laurent Créancier, Stéphanie Lerondel, Alain Le Pape, Christian Recher, Cécile Demur, Nicolas Guilbaud, Anna Kruczynski

published 27 Jan 2012

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The Increased Expression of Integrin α6 (ITGA6) Enhances Drug Resistance in EVI1^high Leukemia

Norio Yamakawa, Kazuko Kaneda, Yusuke Saito, Emi Ichihara, Kazuhiro Morishita

published 25 Jan 2012

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Lapatinib Induces Autophagy, Apoptosis and Megakaryocytic Differentiation in Chronic Myelogenous Leukemia K562 Cells

Huey-Lan Huang, Yu-Chieh Chen, Yu-Chuen Huang, Kai-Chien Yang, Hsin yi Pan, Shou-Ping Shih, Yu-Jen Chen

published 22 Dec 2011

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A Two-Gene Signature, SKI and SLAMF1, Predicts Time-to-Treatment in Previously Untreated Patients with Chronic Lymphocytic Leukemia

Carmen D. Schweighofer, Kevin R. Coombes, Lynn L. Barron, Lixia Diao, Rachel J. Newman, Alessandra Ferrajoli, Susan O'Brien, William G. Wierda, Rajyalakshmi Luthra, L. Jeffrey Medeiros, Michael J. Keating, Lynne V. Abruzzo

published 14 Dec 2011

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