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Lactones

Mode of Action of the Sesquiterpene Lactones Psilostachyin and Psilostachyin C on Trypanosoma cruzi

Valeria P. Sülsen, Vanesa Puente, Daniela Papademetrio, Alcira Batlle, Virginia S. Martino, Fernanda M. Frank, María E. Lombardo

published 03 Mar 2016

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Toward Understanding the Catalytic Mechanism of Human Paraoxonase 1: Site-Specific Mutagenesis at Position 192

Geetika Aggarwal, Rameshwar Prajapati, Rajan K. Tripathy, Priyanka Bajaj, A. R. Satvik Iyengar, Abhay T. Sangamwar, Abhay H. Pande

published 01 Feb 2016

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Curiouser and Curiouser: The Macrocyclic Lactone, Abamectin, Is also a Potent Inhibitor of Pyrantel/Tribendimidine Nicotinic Acetylcholine Receptors of Gastro-Intestinal Worms

Melanie Abongwa, Samuel K. Buxton, Alan P. Robertson, Richard J. Martin

published 11 Jan 2016

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Chemo-Enzymatic Synthesis of Optically Active γ- and δ-Decalactones and Their Effect on Aphid Probing, Feeding and Settling Behavior

Filip Boratyński, Katarzyna Dancewicz, Marlena Paprocka, Beata Gabryś, Czesław Wawrzeńczyk

published 07 Jan 2016

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An Engineered Version of Human PON2 Opens the Way to Understand the Role of Its Post-Translational Modifications in Modulating Catalytic Activity

Luigi Mandrich, Mariangela Cerreta, Giuseppe Manco

published 10 Dec 2015

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Natural Guided Genome Engineering Reveals Transcriptional Regulators Controlling Quorum-Sensing Signal Degradation

Abbas El Sahili, Anthony Kwasiborski, Nicolas Mothe, Christophe Velours, Pierre Legrand, Solange Moréra, Denis Faure

published 10 Nov 2015

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Synthesis and Antifeedant Activity of Racemic and Optically Active Hydroxy Lactones with the p-Menthane System

Aleksandra Grudniewska, Marek Kłobucki, Katarzyna Dancewicz, Maryla Szczepanik, Beata Gabryś, Czesław Wawrzeńczyk

published 01 Jul 2015

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In Silico and In Vitro Analysis of Bacoside A Aglycones and Its Derivatives as the Constituents Responsible for the Cognitive Effects of Bacopa monnieri

Seetha Ramasamy, Sek Peng Chin, Sri Devi Sukumaran, Michael James Christopher Buckle, Lik Voon Kiew, Lip Yong Chung

published 12 May 2015

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Molecular Structure-Affinity Relationship of Bufadienolides and Human Serum Albumin In Vitro and Molecular Docking Analysis

Jing Zhou, Guodi Lu, Honglan Wang, Junfeng Zhang, Jinao Duan, Hongyue Ma, Qinan Wu

published 06 May 2015

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Active Site Loop Conformation Regulates Promiscuous Activity in a Lactonase from Geobacillus kaustophilus HTA426

Yu Zhang, Jiao An, Guang-Yu Yang, Aixi Bai, Baisong Zheng, Zhiyong Lou, Geng Wu, Wei Ye, Hai-Feng Chen, Yan Feng, Giuseppe Manco

published 23 Feb 2015

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Gentiolactone, a Secoiridoid Dilactone from Gentiana triflora, Inhibits TNF-α, iNOS and Cox-2 mRNA Expression and Blocks NF-κB Promoter Activity in Murine Macrophages

Hidetoshi Yamada, Sayaka Kikuchi, Tomoki Inui, Hideyuki Takahashi, Ken-ichi Kimura

published 25 Nov 2014

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Evolution of Acyl-Substrate Recognition by a Family of Acyl-Homoserine Lactone Synthases

Quin H. Christensen, Ryan M. Brecht, Dastagiri Dudekula, E. Peter Greenberg, Rajesh Nagarajan

published 17 Nov 2014

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21-Benzylidene Digoxin: A Proapoptotic Cardenolide of Cancer Cells That Up-Regulates Na,K-ATPase and Epithelial Tight Junctions

Sayonarah C. Rocha, Marco T. C. Pessoa, Luiza D. R. Neves, Silmara L. G. Alves, Luciana M. Silva, Herica L. Santos, Soraya M. F. Oliveira, Alex G. Taranto, Moacyr Comar, Isabella V. Gomes, Fabio V. Santos, Natasha Paixão, Luis E. M. Quintas, François Noël, Antonio F. Pereira, Ana C. S. C. Tessis, Natalia L. S. Gomes, Otacilio C. Moreira, Ruth Rincon-Heredia, Fernando P. Varotti, Gustavo Blanco, Jose A. F. P. Villar, Rubén G. Contreras, Leandro A. Barbosa

published 07 Oct 2014

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