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Isozymes

Crystal Structure of Human AKT1 with an Allosteric Inhibitor Reveals a New Mode of Kinase Inhibition

Wen-I Wu, Walter C. Voegtli, [ ... ], Barbara J. Brandhuber

Multiplicity of Steady States in Glycolysis and Shift of Metabolic State in Cultured Mammalian Cells

Bhanu Chandra Mulukutla, Andrew Yongky, [ ... ], Wei-Shou Hu

Differential Scanning Fluorometry Signatures as Indicators of Enzyme Inhibitor Mode of Action: Case Study of Glutathione S-Transferase

Wendy A. Lea, Anton Simeonov

Bistability in Glycolysis Pathway as a Physiological Switch in Energy Metabolism

Bhanu Chandra Mulukutla, Andrew Yongky, Prodromos Daoutidis, Wei-Shou Hu

Metabolic Profiling of Alternative NAD Biosynthetic Routes in Mouse Tissues

Valerio Mori, Adolfo Amici, [ ... ], Giuseppe Orsomando

Long Term Effect of Curcumin in Restoration of Tumour Suppressor p53 and Phase-II Antioxidant Enzymes via Activation of Nrf2 Signalling and Modulation of Inflammation in Prevention of Cancer

Laxmidhar Das, Manjula Vinayak

Integrative taxonomy of root-knot nematodes reveals multiple independent origins of mitotic parthenogenesis

Toon Janssen, Gerrit Karssen, [ ... ], Wim Bert

Catalytic Signature of a Heat-Stable, Chimeric Human Alkaline Phosphatase with Therapeutic Potential

Tina Kiffer-Moreira, Campbell R. Sheen, [ ... ], José Luis Millán

Rift Valley Fever Virus Infection of Human Cells and Insect Hosts Is Promoted by Protein Kinase C Epsilon

Claire Marie Filone, Sheri L. Hanna, [ ... ], Sara Cherry

Identification of individual components of a commercial wheat germ acid phosphatase preparation

Veronica R. Moorman, Alexandra M. Brayton

A Novel Lentinula edodes Laccase and Its Comparative Enzymology Suggest Guaiacol-Based Laccase Engineering for Bioremediation

Kin-Sing Wong, Man-Kit Cheung, Chun-Hang Au, Hoi-Shan Kwan

SAHA Enhances Synaptic Function and Plasticity In Vitro but Has Limited Brain Availability In Vivo and Does Not Impact Cognition

Jesse E. Hanson, Hank La, [ ... ], Qiang Zhou

A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

Adam Yasgar, Steven A. Titus, [ ... ], Natalia J. Martinez

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