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Interferons

Innate Immune Response of Human Plasmacytoid Dendritic Cells to Poxvirus Infection Is Subverted by Vaccinia E3 via Its Z-DNA/RNA Binding Domain

Hua Cao, Peihong Dai, Weiyi Wang, Hao Li, Jianda Yuan, Fangjin Wang, Chee-Mun Fang, Paula M Pitha, Jia Liu, Richard C Condit, Grant McFadden, Taha Merghoub, Alan N Houghton, James W Young, Stewart Shuman, Liang Deng

published 14 May 2012

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High Throughput Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery

Dhara A. Patel, Anand C. Patel, William C. Nolan, Yong Zhang, Michael J. Holtzman

published 04 May 2012

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Oncolytic Effects of a Novel Influenza A Virus Expressing Interleukin-15 from the NS Reading Frame

Marijke van Rikxoort, Martin Michaelis, Markus Wolschek, Thomas Muster, Andrej Egorov, Joachim Seipelt, Hans Wilhelm Doerr, Jindrich Cinatl Jr

published 01 May 2012

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IFN-λ3 Inhibits HIV Infection of Macrophages through the JAK-STAT Pathway

Man-Qing Liu, Dun-Jin Zhou, Xu Wang, Wang Zhou, Li Ye, Jie-Liang Li, Yi-Zhong Wang, Wen-Zhe Ho

published 27 Apr 2012

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Uterine Epithelial Cells Specifically Induce Interferon-Stimulated Genes in Response to Polyinosinic-Polycytidylic Acid Independently of Estradiol

Mickey V. Patel, Mimi Ghosh, John V. Fahey, Charles R. Wira

published 25 Apr 2012

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Dobrava-Belgrade Hantavirus from Germany Shows Receptor Usage and Innate Immunity Induction Consistent with the Pathogenicity of the Virus in Humans

Elena Popugaeva, Peter T. Witkowski, Mathias Schlegel, Rainer G. Ulrich, Brita Auste, Andreas Rang, Detlev H. Krüger, Boris Klempa

published 24 Apr 2012

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Genetic Resistance to Rhabdovirus Infection in Teleost Fish Is Paralleled to the Derived Cell Resistance Status

Eloi R. Verrier, Christelle Langevin, Corinne Tohry, Armel Houel, Vincent Ducrocq, Abdenour Benmansour, Edwige Quillet, Pierre Boudinot

published 13 Apr 2012

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Spherical Lactic Acid Bacteria Activate Plasmacytoid Dendritic Cells Immunomodulatory Function via TLR9-Dependent Crosstalk with Myeloid Dendritic Cells

Kenta Jounai, Kumiko Ikado, Tetsu Sugimura, Yasuhisa Ano, Jonathan Braun, Daisuke Fujiwara

published 10 Apr 2012

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RNA Sensors Enable Human Mast Cell Anti-Viral Chemokine Production and IFN-Mediated Protection in Response to Antibody-Enhanced Dengue Virus Infection

Michael G. Brown, Sarah M. McAlpine, Yan Y. Huang, Ian D. Haidl, Ayham Al-Afif, Jean S. Marshall, Robert Anderson

published 30 Mar 2012

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Tyrosine Phosphorylation of the E3 Ubiquitin Ligase TRIM21 Positively Regulates Interaction with IRF3 and Hence TRIM21 Activity

Kevin B. Stacey, Eamon Breen, Caroline A. Jefferies

published 30 Mar 2012

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Sialylation of Campylobacter jejuni Lipo-Oligosaccharides: Impact on Phagocytosis and Cytokine Production in Mice

Ruth Huizinga, Alistair S. Easton, Anne M. Donachie, Jim Guthrie, Wouter van Rijs, Astrid Heikema, Louis Boon, Janneke N. Samsom, Bart C. Jacobs, Hugh J. Willison, Carl S. Goodyear

published 28 Mar 2012

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Chronic Immune Activation in HIV-1 Infection Contributes to Reduced Interferon Alpha Production via Enhanced CD40:CD40 Ligand Interaction

Norbert Donhauser, Kathrin Pritschet, Martin Helm, Thomas Harrer, Philipp Schuster, Moritz Ries, Georg Bischof, Jörg Vollmer, Sigrun Smola, Barbara Schmidt, for the German Competence Network HIV/AIDS

published 21 Mar 2012

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Activation of Type I and III Interferon Signalling Pathways Occurs in Lung Epithelial Cells Infected with Low Pathogenic Avian Influenza Viruses

Richard Sutejo, Dawn S. Yeo, Myint Zu Myaing, Chen Hui, Jiajia Xia, Debbie Ko, Peter C. F. Cheung, Boon-Huan Tan, Richard J. Sugrue

published 21 Mar 2012

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