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Integrins

Gelatin coating enhances therapeutic cell adhesion to the infarcted myocardium via ECM binding

Kara A. Davis, Anuhya Gottipatti, Hsuan Peng, Renee Donahue, Lakshman Chelvarajan, Calvin Cahall, Himi Tripathi, Ahmed Al-Darraji, Shaojing Ye, Ahmed Abdel-Latif, Brad J. Berron

published 10 Nov 2022

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An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family

Céline Cegarra, Béatrice Cameron, Catarina Chaves, Tarik Dabdoubi, Tuan-Minh Do, Bruno Genêt, Valérie Roudières, Yi Shi, Patricia Tchepikoff, Dominique Lesuisse

published 15 Sep 2022

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Cyclical depressurization degranulates platelets in an agonist-free mechanism of platelet activation

Aaron J. Velasquez-Mao, Mark Velasquez, Moriel H. Vandsburger

published 15 Sep 2022

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Evaluation of sperm integrin α5β1 as a potential marker of fertility in humans

Zoilo José Vernaz, Raquel María Lottero-Leconte, Carlos Agustín Isidro Alonso, Sofía Rio, Maia Florencia Morales, Camila Arroyo-Salvo, Carla C. Valiente, María Lovaglio Diez, María Eugenia Bogetti, Gabriela Arenas, Gastón Rey-Valzacchi, Silvina Perez-Martinez

published 02 Aug 2022

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Trpc6 gain-of-function disease mutation enhances phosphatidylserine exposure in murine platelets

Kimber L. Boekell, Brittney J. Brown, Brianna E. Talbot, Johannes S. Schlondorff

published 24 Jun 2022

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Transcriptomic analysis reveals high ITGB1 expression as a predictor for poor prognosis of pancreatic cancer

Yosuke Iwatate, Hajime Yokota, Isamu Hoshino, Fumitaka Ishige, Naoki Kuwayama, Makiko Itami, Yasukuni Mori, Satoshi Chiba, Hidehito Arimitsu, Hiroo Yanagibashi, Wataru Takayama, Takashi Uno, Jason Lin, Yuki Nakamura, Yasutoshi Tatsumi, Osamu Shimozato, Hiroki Nagase

published 01 Jun 2022

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Complex protein interactions mediate Drosophila Lar function in muscle tissue

Jessica Kawakami, David Brooks, Rana Zalmai, Steven D. Hartson, Samuel Bouyain, Erika R. Geisbrecht

published 27 May 2022

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Endotoxin-induced acute lung injury in mice with postnatal deletion of nephronectin

Carole L. Wilson, Chi F. Hung, Lynn M. Schnapp

published 12 May 2022

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Vitronectin-derived bioactive peptide prevents spondyloarthritis by modulating Th17/Treg imbalance in mice with curdlan-induced spondyloarthritis

Hong Ki Min, JeongWon Choi, Seon-Yeong Lee, A. Ram Lee, Byung-Moo Min, Mi-La Cho, Sung-Hwan Park

published 05 Jan 2022

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Tumor Necrosis Factor-alpha utilizes MAPK/NFκB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway

Swechha M. Pokharel, Kim Chiok, Niraj K. Shil, Indira Mohanty, Santanu Bose

published 22 Sep 2021

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BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1

Zsuzsa Nagy-Baló, Richárd Kiss, Judit Demeter, Csaba Bödör, Zsuzsa Bajtay, Anna Erdei

published 20 Jul 2021

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Comparative use of CRISPR and RNAi to modulate integrin α3β1 in triple negative breast cancer cells reveals that some pro-invasive/pro-metastatic α3β1 functions are independent of global regulation of the transcriptome

James Kenney, Abibatou Ndoye, John M. Lamar, C. Michael DiPersio

published 16 Jul 2021

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SARS-CoV-2 uses major endothelial integrin αvβ3 to cause vascular dysregulation in-vitro during COVID-19

Danielle Nader, Nicola Fletcher, Gerard F. Curley, Steven W. Kerrigan

published 23 Jun 2021

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