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Integrins

Gelatin coating enhances therapeutic cell adhesion to the infarcted myocardium via ECM binding

Kara A. Davis, Anuhya Gottipatti, [ ... ], Brad J. Berron

An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family

Céline Cegarra, Béatrice Cameron, [ ... ], Dominique Lesuisse

Cyclical depressurization degranulates platelets in an agonist-free mechanism of platelet activation

Aaron J. Velasquez-Mao, Mark Velasquez, Moriel H. Vandsburger

Evaluation of sperm integrin α5β1 as a potential marker of fertility in humans

Zoilo José Vernaz, Raquel María Lottero-Leconte, [ ... ], Silvina Perez-Martinez

Trpc6 gain-of-function disease mutation enhances phosphatidylserine exposure in murine platelets

Kimber L. Boekell, Brittney J. Brown, Brianna E. Talbot, Johannes S. Schlondorff

Transcriptomic analysis reveals high ITGB1 expression as a predictor for poor prognosis of pancreatic cancer

Yosuke Iwatate, Hajime Yokota, [ ... ], Hiroki Nagase

Complex protein interactions mediate Drosophila Lar function in muscle tissue

Jessica Kawakami, David Brooks, [ ... ], Erika R. Geisbrecht

Endotoxin-induced acute lung injury in mice with postnatal deletion of nephronectin

Carole L. Wilson, Chi F. Hung, Lynn M. Schnapp

Vitronectin-derived bioactive peptide prevents spondyloarthritis by modulating Th17/Treg imbalance in mice with curdlan-induced spondyloarthritis

Hong Ki Min, JeongWon Choi, [ ... ], Sung-Hwan Park

Tumor Necrosis Factor-alpha utilizes MAPK/NFκB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway

Swechha M. Pokharel, Kim Chiok, [ ... ], Santanu Bose

BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1

Zsuzsa Nagy-Baló, Richárd Kiss, [ ... ], Anna Erdei

Comparative use of CRISPR and RNAi to modulate integrin α3β1 in triple negative breast cancer cells reveals that some pro-invasive/pro-metastatic α3β1 functions are independent of global regulation of the transcriptome

James Kenney, Abibatou Ndoye, John M. Lamar, C. Michael DiPersio

SARS-CoV-2 uses major endothelial integrin αvβ3 to cause vascular dysregulation in-vitro during COVID-19

Danielle Nader, Nicola Fletcher, Gerard F. Curley, Steven W. Kerrigan

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