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Insulitis

Type 1 Diabetes Prevention in NOD Mice by Targeting DPPIV/CD26 Is Associated with Changes in CD8⁺T Effector Memory Subset

Núria Alonso, María Teresa Julián, Jorge Carrascal, Roger Colobran, Irma Pujol-Autonell, Silvia Rodriguez-Fernández, Aina Teniente, Marco Antonio Fernández, Antoni Miñarro, María Carmen Ruiz de Villa, Marta Vives-Pi, Manel Puig-Domingo

published 10 Nov 2015

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Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes

Tomoko Hayashi, Shiyin Yao, Brian Crain, Victor J. Promessi, Luke Shyu, Caroline Sheng, McNancy Kang, Howard B. Cottam, Dennis A. Carson, Maripat Corr

published 15 Jun 2015

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Use of Autoantigen-Loaded Phosphatidylserine-Liposomes to Arrest Autoimmunity in Type 1 Diabetes

Irma Pujol-Autonell, Arnau Serracant-Prat, Mary Cano-Sarabia, Rosa M. Ampudia, Silvia Rodriguez-Fernandez, Alex Sanchez, Cristina Izquierdo, Thomas Stratmann, Manuel Puig-Domingo, Daniel Maspoch, Joan Verdaguer, Marta Vives-Pi

published 03 Jun 2015

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The Dual Role of Scavenger Receptor Class A in Development of Diabetes in Autoimmune NOD Mice

Mami Shimizu, Hisafumi Yasuda, Kenta Hara, Kazuma Takahashi, Masao Nagata, Koichi Yokono

published 24 Oct 2014

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Combining MK626, a Novel DPP-4 Inhibitor, and Low-Dose Monoclonal CD3 Antibody for Stable Remission of New-Onset Diabetes in Mice

Lei Ding, Conny A. Gysemans, Geert Stangé, Yves Heremans, Yixing Yuchi, Tatiana Takiishi, Hannelie Korf, Marie Chintinne, Richard D. Carr, Harry Heimberg, Daniel Pipeleers, Chantal Mathieu

published 30 Sep 2014

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Autoimmune Diabetes Is Suppressed by Treatment with Recombinant Human Tissue Kallikrein-1

Lilia Maneva-Radicheva, Christina Amatya, Camille Parker, Jacob Ellefson, Ilian Radichev, Arvind Raghavan, Matthew L. Charles, Mark S. Williams, Mark S. Robbins, Alexei Y. Savinov

published 26 Sep 2014

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The Gene Expression Profile of CD11c⁺CD8α⁻ Dendritic Cells in the Pre-Diabetic Pancreas of the NOD Mouse

Wouter Beumer, Jojanneke M. C. Welzen-Coppens, Cornelia G. van Helden-Meeuwsen, Sinead M. Gibney, Hemmo A. Drexhage, Marjan A. Versnel

published 28 Aug 2014

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Oral Administration of Recombinant Lactococcus lactis Expressing HSP65 and Tandemly Repeated P277 Reduces the Incidence of Type I Diabetes in Non-Obese Diabetic Mice

Yanjun Ma, Jingjing Liu, Jing Hou, Yuankai Dong, Yong Lu, Liang Jin, Rongyue Cao, Taiming Li, Jie Wu

published 26 Aug 2014

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Islet Remodeling in Female Mice with Spontaneous Autoimmune and Streptozotocin-Induced Diabetes

Annette Plesner, Joris T. ten Holder, C. Bruce Verchere

published 07 Aug 2014

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Prevention or Early Cure of Type 1 Diabetes by Intranasal Administration of Gliadin in NOD Mice

David P. Funda, Petra Fundova, Axel Kornerup Hansen, Karsten Buschard

published 11 Apr 2014

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Tissue-Specific Methylation of Human Insulin Gene and PCR Assay for Monitoring Beta Cell Death

Mohamed I. Husseiny, Alexander Kaye, Emily Zebadua, Fouad Kandeel, Kevin Ferreri

published 10 Apr 2014

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Protective Effects of Combined Intervention with Adenovirus Vector Mediated IL-10 and IGF-1 Genes on Endogenous Islet β Cells in Nonobese Diabetes Mice with Onset of Type 1 Diabetes Mellitus

Lijuan Zhang, Yanyan Chen, Cheng Li, Xiaojie Lin, Xiaoli Cheng, Tang Li

published 24 Mar 2014

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Blockade of the Programmed Death-1 (PD1) Pathway Undermines Potent Genetic Protection from Type 1 Diabetes

Nora M. Kochupurakkal, Annie J. Kruger, Sudipta Tripathi, Bing Zhu, La Tonya Adams, Daniel B. Rainbow, Aldo Rossini, Dale L. Greiner, Mohamed H. Sayegh, Linda S. Wicker, Indira Guleria

published 28 Feb 2014

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