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Insulin secretion

Mitochondrial Function Is Required for Secretion of DAF-28/Insulin in C. elegans

Ola Billing, Gautam Kao, Peter Naredi

published 17 Jan 2011

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NADPH Oxidase 2-Derived Reactive Oxygen Species Mediate FFAs-Induced Dysfunction and Apoptosis of β-Cells via JNK, p38 MAPK and p53 Pathways

Huiping Yuan, Xiaoyong Zhang, Xiuqing Huang, Yonggang Lu, Weiqing Tang, Yong Man, Shu Wang, Jianzhong Xi, Jian Li

published 29 Dec 2010

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Evaluation of Fasting State-/Oral Glucose Tolerance Test-Derived Measures of Insulin Release for the Detection of Genetically Impaired β-Cell Function

Silke A. Herzberg-Schäfer, Harald Staiger, Martin Heni, Caroline Ketterer, Martina Guthoff, Konstantinos Kantartzis, Fausto Machicao, Norbert Stefan, Hans-Ulrich Häring, Andreas Fritsche

published 02 Dec 2010

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Expression and Regulation of Cyclic Nucleotide Phosphodiesterases in Human and Rat Pancreatic Islets

Emilia Heimann, Helena A. Jones, Svante Resjö, Vincent C. Manganiello, Lena Stenson, Eva Degerman

published 01 Dec 2010

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Neuronal Calcium Sensor Synaptotagmin-9 Is Not Involved in the Regulation of Glucose Homeostasis or Insulin Secretion

Natalia Gustavsson, Xiaorui Wang, Yue Wang, Tingting Seah, Jun Xu, George K. Radda, Thomas C. Südhof, Weiping Han

published 09 Nov 2010

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β2-Syntrophin Is a Cdk5 Substrate That Restrains the Motility of Insulin Secretory Granules

Sandra Schubert, Klaus-Peter Knoch, Joke Ouwendijk, Shabaz Mohammed, Yury Bodrov, Melanie Jäger, Anke Altkrüger, Carolin Wegbrod, Marvin E. Adams, Yong Kim, Stanley C. Froehner, Ole N. Jensen, Yannis Kalaidzidis, Michele Solimena

published 23 Sep 2010

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Novel GLP-1 Fusion Chimera as Potent Long Acting GLP-1 Receptor Agonist

Qinghua Wang, Kui Chen, Rui Liu, Fang Zhao, Sandeep Gupta, Nina Zhang, Gerald J. Prud'homme

published 15 Sep 2010

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Transgenic Overexpression of Active Calcineurin in β-Cells Results in Decreased β-Cell Mass and Hyperglycemia

Ernesto Bernal-Mizrachi, Corentin Cras-Méneur, Bo Ra Ye, James D. Johnson, M. Alan Permutt

published 03 Aug 2010

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A Novel Role for the Centrosomal Protein, Pericentrin, in Regulation of Insulin Secretory Vesicle Docking in Mouse Pancreatic β-cells

Agata Jurczyk, Steven C. Pino, Bryan O'Sullivan-Murphy, Martha Addorio, Erich A. Lidstone, Philip diIorio, Kathryn L. Lipson, Clive Standley, Kevin Fogarty, Lawrence Lifshitz, Fumihiko Urano, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, Rita Bortell

published 27 Jul 2010

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Effects of GCK, GCKR, G6PC2 and MTNR1B Variants on Glucose Metabolism and Insulin Secretion

Cheng Hu, Rong Zhang, Congrong Wang, Weihui Yu, Jingyi Lu, Xiaojing Ma, Jie Wang, Feng Jiang, Shanshan Tang, Yuqian Bao, Kunsan Xiang, Weiping Jia

published 23 Jul 2010

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Common Polymorphisms in MTNR1B, G6PC2 and GCK Are Associated with Increased Fasting Plasma Glucose and Impaired Beta-Cell Function in Chinese Subjects

Claudia Ha Ting Tam, Janice Sin Ka Ho, Ying Wang, Heung Man Lee, Vincent Kwok Lim Lam, Soren Germer, Mitchell Martin, Wing Yee So, Ronald Ching Wan Ma, Juliana Chung Ngor Chan, Maggie Chor Yin Ng

published 08 Jul 2010

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Type 2 Diabetes Susceptibility Gene Expression in Normal or Diabetic Sorted Human Alpha and Beta Cells: Correlations with Age or BMI of Islet Donors

Clare L. Kirkpatrick, Piero Marchetti, Francesco Purrello, Salvatore Piro, Marco Bugliani, Domenico Bosco, Eelco J. P. de Koning, Marten A. Engelse, Julie Kerr-Conte, François Pattou, Claes B. Wollheim

published 10 Jun 2010

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Defective Secretion of Islet Hormones in Chromogranin-B Deficient Mice

Stefanie Obermüller, Federico Calegari, Angus King, Anders Lindqvist, Ingmar Lundquist, Albert Salehi, Maura Francolini, Patrizia Rosa, Patrik Rorsman, Wieland B. Huttner, Sebastian Barg

published 28 Jan 2010

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