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Insulin secretion

A novel strategy for production of liraglutide precursor peptide and development of a new long-acting incretin mimic

Samaneh Ahmadi, Mohammad Bagher Shahsavani, Zohreh Tavaf, Rawayh Muslim Albaghlany, Ashutosh Kumar, Ali Akbar Moosavi-Movahedi, Reza Yousefi

published 02 May 2022

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Adrenomedullin and its receptors are expressed in mouse pancreatic β-cells and suppresses insulin synthesis and secretion

Yuanlin Dong, Simone Hernandez Ruano, Akansha Mishra, Kathleen A. Pennington, Chandrasekhar Yallampalli

published 24 Mar 2022

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Auto-segmentation and time-dependent systematic analysis of mesoscale cellular structure in β-cells during insulin secretion

Angdi Li, Xiangyi Zhang, Jitin Singla, Kate White, Valentina Loconte, Chuanyang Hu, Chuyu Zhang, Shuailin Li, Weimin Li, John Paul Francis, Chenxi Wang, Andrej Sali, Liping Sun, Xuming He, Raymond C. Stevens

published 24 Mar 2022

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Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets

Yasutaka Miyachi, Taiyi Kuo, Jinsook Son, Domenico Accili

published 29 Nov 2021

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SUR1-E1506K mutation impairs glucose tolerance and promotes vulnerable atherosclerotic plaque phenotype in hypercholesterolemic mice

Erika Gurzeler, Anna-Kaisa Ruotsalainen, Anssi Laine, Teemu Valkama, Sanna Kettunen, Markku Laakso, Seppo Ylä-Herttuala

published 12 Nov 2021

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Reproducibility and discrimination of different indices of insulin sensitivity and insulin secretion

Sarah Hudak, Philipp Huber, Apostolia Lamprinou, Louise Fritsche, Norbert Stefan, Andreas Peter, Andreas L. Birkenfeld, Andreas Fritsche, Martin Heni, Robert Wagner

published 22 Oct 2021

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Cyanidin-3-O-Glucoside improves the viability of human islet cells treated with amylin or Aβ_1-42 in vitro

Jennifer Croden, Josue Rodrigues Silva, Wenlong Huang, Nancy Gupta, Wen Fu, Kaja Matovinovic, Mazzen Black, Xian Li, Kunsong Chen, Yulian Wu, Jack Jhamandas, Gina R. Rayat

published 06 Oct 2021

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Microtubules and Gαo-signaling modulate the preferential secretion of young insulin secretory granules in islet β cells via independent pathways

Ruiying Hu, Xiaodong Zhu, Mingyang Yuan, Kung-Hsien Ho, Irina Kaverina, Guoqiang Gu

published 22 Jul 2021

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Neuromedin U uses Gα_i2 and Gα_o to suppress glucose-stimulated Ca²⁺ signaling and insulin secretion in pancreatic β cells

Weidong Zhang, Hideyuki Sakoda, Yuki Nakazato, Md Nurul Islam, François Pattou, Julie Kerr-Conte, Masamitsu Nakazato

published 15 Apr 2021

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Flipping the switch on the hub cell: Islet desynchronization through cell silencing

Janita P. Hogan, Bradford E. Peercy

published 08 Apr 2021

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Impact of 1h oral glucose tolerance test on the clinical status of adult cystic fibrosis patients over a 4-year period

Valérie Boudreau, Quitterie Reynaud, Angélique Denis, Johann Colomba, Sandrine Touzet, Katherine Desjardins, Stéphanie Poupon Bourdy, Isabelle Durieu, Rémi Rabasa-Lhoret

published 18 Mar 2021

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Transcriptional analysis of islets of Langerhans from organ donors of different ages

Peter Seiron, Anton Stenwall, Anders Hedin, Louise Granlund, Jonathan Lou S. Esguerra, Petr Volkov, Erik Renström, Olle Korsgren, Marcus Lundberg, Oskar Skog

published 12 Mar 2021

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Imeglimin amplifies glucose-stimulated insulin release from diabetic islets via a distinct mechanism of action

Sophie Hallakou-Bozec, Micheline Kergoat, Pascale Fouqueray, Sébastien Bolze, David E. Moller

published 19 Feb 2021

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