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Innate immune system

High Pro-Inflammatory Cytokine Secretion and Loss of High Avidity Cross-Reactive Cytotoxic T-Cells during the Course of Secondary Dengue Virus Infection

Tao Dong, Edward Moran, Nguyen Vinh Chau, Cameron Simmons, Kerstin Luhn, Yanchun Peng, Bridget Wills, Nguyen Phuong Dung, Le Thi Thu Thao, Tran Tinh Hien, Andrew McMichael, Jeremy Farrar, Sarah Rowland-Jones

published 05 Dec 2007

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A Major Ingredient of Green Tea Rescues Mice from Lethal Sepsis Partly by Inhibiting HMGB1

Wei Li, Mala Ashok, Jianhua Li, Huan Yang, Andrew E. Sama, Haichao Wang

published 07 Nov 2007

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Functional Inactivation of EBV-Specific T-Lymphocytes in Nasopharyngeal Carcinoma: Implications for Tumor Immunotherapy

Jiang Li, Xue-hui Zeng, Hao-yuan Mo, Ulrika Rolén, Yan-fang Gao, Xiao-shi Zhang, Qiu-yan Chen, Li Zhang, Mu-sheng Zeng, Man-zhi Li, Wen-lin Huang, Xiao-ning Wang, Yi-Xin Zeng, Maria G. Masucci

published 07 Nov 2007

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Therapeutic Effect of a Poly(ADP-Ribose) Polymerase-1 Inhibitor on Experimental Arthritis by Downregulating Inflammation and Th1 Response

Elena Gonzalez-Rey, Ruben Martínez-Romero, Francisco O'Valle, Rocío Aguilar-Quesada, Carmen Conde, Mario Delgado, F. Javier Oliver

published 31 Oct 2007

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Gene Expression Signature in Peripheral Blood Detects Thoracic Aortic Aneurysm

Yulei Wang, Catalin C. Barbacioru, Dov Shiffman, Sriram Balasubramanian, Olga Iakoubova, Maryann Tranquilli, Gonzalo Albornoz, Julie Blake, Necip N. Mehmet, Dewi Ngadimo, Karen Poulter, Frances Chan, Raymond R. Samaha, John A. Elefteriades

published 17 Oct 2007

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Murine Gammaherpesvirus-68 Inhibits Antigen Presentation by Dendritic Cells

Christopher M. Smith, Michael B. Gill, Janet S. May, Philip G. Stevenson

published 17 Oct 2007

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Severe Respiratory Syncytial Virus Bronchiolitis in Infants Is Associated with Reduced Airway Interferon Gamma and Substance P

Malcolm G. Semple, Hinke M. Dankert, Bahram Ebrahimi, Jailson B. Correia, J. Angela Booth, James P. Stewart, Rosalind L. Smyth, C. Anthony Hart

published 17 Oct 2007

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Phenotypic Studies of Natural Killer Cell Subsets in Human Transporter Associated with Antigen Processing Deficiency

Jacques Zimmer, Huguette Bausinger, Emmanuel Andrès, Lionel Donato, Daniel Hanau, François Hentges, Alessandro Moretta, Henri de la Salle

published 17 Oct 2007

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Endothelial Progenitor Cells, Cardiovascular Risk Factors, Cytokine Levels and Atherosclerosis – Results from a Large Population-Based Study

Qingzhong Xiao, Stefan Kiechl, Seema Patel, Friedrich Oberhollenzer, Siegfried Weger, Agnes Mayr, Bernhard Metzler, Markus Reindl, Yanhua Hu, Johann Willeit, Qingbo Xu

published 10 Oct 2007

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Human Neonatal Dendritic Cells Are Competent in MHC Class I Antigen Processing and Presentation

Marielle C. Gold, Tammie L. Robinson, Matthew S. Cook, Laura K. Byrd, Heather D. Ehlinger, David M. Lewinsohn, Deborah A. Lewinsohn

published 26 Sep 2007

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Digital NFATc2 Activation per Cell Transforms Graded T Cell Receptor Activation into an All-or-None IL-2 Expression

Miriam Podtschaske, Uwe Benary, Sandra Zwinger, Thomas Höfer, Andreas Radbruch, Ria Baumgrass

published 26 Sep 2007

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Endocytosis of DNA-Hsp65 Alters the pH of the Late Endosome/Lysosome and Interferes with Antigen Presentation

Ana Paula F. Trombone, Célio L. Silva, Karla M. Lima, Constance Oliver, Maria Célia Jamur, Alan R. Prescott, Arlete A. M. Coelho-Castelo

published 26 Sep 2007

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Targeted Deletion of HIF-1α Gene in T Cells Prevents their Inhibition in Hypoxic Inflamed Tissues and Improves Septic Mice Survival

Manfred Thiel, Charles C. Caldwell, Simone Kreth, Satoshi Kuboki, P. Chen, Patrick Smith, Akio Ohta, Alex B. Lentsch, Dmitry Lukashev, Michail V. Sitkovsky

published 05 Sep 2007

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