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Innate immune system

Identification of Benzimidazole Diamides as Selective Inhibitors of the Nucleotide-Binding Oligomerization Domain 2 (NOD2) Signaling Pathway

David J. Rickard, Clark A. Sehon, [ ... ], John Bertin

The IL23R R381Q Gene Variant Protects against Immune-Mediated Diseases by Impairing IL-23-Induced Th17 Effector Response in Humans

Paola Di Meglio, Antonella Di Cesare, [ ... ], Frank O. Nestle

Signal 3 Cytokines as Modulators of Primary Immune Responses during Infections: The Interplay of Type I IFN and IL-12 in CD8 T Cell Responses

Selina Jessica Keppler, Kerstin Rosenits, [ ... ], Peter Aichele

Zwitterionic Chitosan Derivative, a New Biocompatible Pharmaceutical Excipient, Prevents Endotoxin-Mediated Cytokine Release

Gaurav Bajaj, William G. Van Alstine, Yoon Yeo

Sarcoptes scabiei Mites Modulate Gene Expression in Human Skin Equivalents

Marjorie S. Morgan, Larry G. Arlian, Michael P. Markey

Cross-linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFNγ/CXCL10-dependent peripheral T cell recruitment in humanized murine model

Floriana Cremasco, Elena Menietti, [ ... ], Mario Perro

A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis

Nina Fransén-Pettersson, Nadia Duarte, [ ... ], Dan Holmberg

Genomic Expression Analyses Reveal Lysosomal, Innate Immunity Proteins, as Disease Correlates in Murine Models of a Lysosomal Storage Disorder

Md. Suhail Alam, Michelle Getz, [ ... ], Kasturi Haldar

Pro-inflammatory, Th1, Th2, Th17 Cytokines and Dendritic Cells: A Cross-sectional Study in Chronic Periodontitis

Giovanna Ribeiro Souto, Celso Martins Queiroz-Junior, [ ... ], Ricardo Alves Mesquita

TNFα alters occludin and cerebral endothelial permeability: Role of p38MAPK

Yawen Ni, Tao Teng, [ ... ], James C. Lee

Residual Endotoxin Contaminations in Recombinant Proteins Are Sufficient to Activate Human CD1c⁺ Dendritic Cells

Harald Schwarz, Maria Schmittner, Albert Duschl, Jutta Horejs-Hoeck

Adiponectin Agonist ADP355 Attenuates CCl₄-Induced Liver Fibrosis in Mice

Pradeep Kumar, Tekla Smith, [ ... ], Frank A. Anania

In Vitro Effects of Pirfenidone on Cardiac Fibroblasts: Proliferation, Myofibroblast Differentiation, Migration and Cytokine Secretion

Qiang Shi, Xiaoyan Liu, [ ... ], Yingjie Wei

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