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Innate immune system

PVAT-conditioned media from Dahl S rats on high fat diet promotes inflammatory cytokine secretion by activated T cells prior to the development of hypertension

Yining Jin, Sheng Liu, [ ... ], Cheryl E. Rockwell

Energy demanding RNA and protein metabolism drive dysfunctionality of HIV-specific T cell changes during chronic HIV infection

Lisa van Pul, Melissa Stunnenberg, [ ... ], Neeltje A. Kootstra

The heat shock protein 90 inhibitor RGRN-305 attenuates SARS-CoV-2 spike protein-induced inflammation in vitro but lacks effectiveness as COVID-19 treatment in mice

Hakim Ben Abdallah, Giorgia Marino, [ ... ], Claus Johansen

Lawsonia intracellularis regulates nuclear factor-κB signalling pathway during infection

Huan W. Yang, Tuanjun Hu, Tahar Ait-Ali

Advancing one health vaccination: In silico design and evaluation of a multi-epitope subunit vaccine against Nipah virus for cross-species immunization using immunoinformatics and molecular modeling

Edward Coralde Banico, Ella Mae Joy Sinco Sira, [ ... ], Fredmoore Legaspi Orosco

TFAB002s, novel CD20-targeting T cell-dependent bispecific Fab-FabCH3 antibodies, exhibit potent antitumor efficacy against malignant B-cell lymphoma

Qinghong Li, Kunming Zhang, [ ... ], Hongyuan Liang

In vitro toxicity assessment of bioavailable iron in coal varieties of Central India

Ruchika Kishor Jain, Anshumali, [ ... ], Bibhuti Bhusan Mandal

PDE5 inhibitor potentially improves polyuria and bladder storage and voiding dysfunctions in type 2 diabetic rats

Takafumi Kabuto, So Inamura, [ ... ], Naoki Terada

Geniposide ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β/Smad and p38MAPK signaling pathways

Jian-Bin Yin, Ying-Xia Wang, [ ... ], Xuan Zhang

Curcumin alleviates heatstroke-induced liver injury in dry-heat environments by inhibiting the expression of NF-κB, iNOS, and ICAM-1 in rats

Xinyue Yang, Liang Xia, [ ... ], Jiangwei Liu

Efficacy and safety of berberine plus 5-ASA for ulcerative colitis: A systematic review and meta-analysis

Jilei Li, Chenchen Zhang, Yanchao Xu, Lili Yang

Acute blood loss in mice forces differentiation of both CD45-positive and CD45-negative erythroid cells and leads to a decreased CCL3 chemokine production by bone marrow erythroid cells

Kirill Nazarov, Roman Perik-Zavodskii, [ ... ], Sergey Sennikov

Assessment of the antileishmanial activity of diallyl sulfide combined with meglumine antimoniate on Leishmania major: Molecular docking, in vitro, and animal model

Farzaneh Zarrinkar, Iraj Sharifi, [ ... ], Mehdi Bamorovat

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