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Innate immune system

Protocol of a mixed (Retrospective and Prospective) longitudinal observational study of amiodarone for chronic Chagas cardiomyopathy (AMIO-CHAGAS study): Investigating immunomodulatory and trypanocidal effects

Juliana Magalhães Chaves Barbosa, Amanda Faier-Pereira, Alejandro Marcel Hasslocher-Moreno, Andréa Rodrigues Costa, Evelyn Nunes Goulart da Silva Pereira, Fernanda de Souza Nogueira Sardinha Mendes, Gilberto Marcelo Sperandio da Silva, Luiz Henrique Conde Sangenis, Marcelo Teixeira Holanda, Mauro Felippe Felix Mediano, Roberto Magalhães Saraiva, Sérgio Salles Xavier, Otacílio da Cruz Moreira, Anissa Daliry, Henrique Horta Veloso, Kelly Salomão

published 28 Apr 2026

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A single dose of purified human antibody from transchromosomic bovines mitigates aerosolized Venezuelan equine encephalitis virus disease in cynomolgus macaques

Chengqun Sun, Christina Gardner, Long Kwan Metthew Lam, Jeneveve Lundy, Katherine O’Malley, Thomas Luke, Kanakatte Raviprakash, Amy L. Hartman, Nicholas A. Crossland, Hua Wu, Jin-an Jiao, Christoph Bausch, Eddie Sullivan, Douglas S. Reed, William B. Klimstra

published 27 Apr 2026

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Distinct tumor genomic signatures underlie canine macrophage polarization

Rachel V. Brady, Sunetra Das, Dawn L. Duval, Kristen B. Farrell, Eric P. Palmer, Douglas H. Thamm

published 24 Apr 2026

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Antitumoral immunity induced by gel ethanol ablation to treat unresectable colorectal cancer metastases in the liver

Jeffrey Yang, Robert Morhard, Hannah Huth, Baktiar Karim, John W. Karanian, Bradford J. Wood, Andrew S. Mikhail, Jenna L. Mueller

published 22 Apr 2026

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Biomaterial-associated molecular patterns (BAMPs) modulate macrophage polarization in bone grafting

Carel Brigi, Mawieh Hamad, Ensanya Ali Abou Neel, Balachandar Selvakumar, K. G. Aghila Rani, Sausan AlKawas, Hamza M. Al Hroub, Sherlyn Jemimah, Amin F. Majdalawieh, Amjad Mahasneh, A. R. Samsudin

published 21 Apr 2026

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A kappa opioid receptor agonist, difelikefalin, improves acute kidney injury in experimental sepsis models

Yoshiharu Sawanobori, Daisuke Nakano, Hiroaki Kitamura, Kento Kitada, Takehiko Asaga, Norio Suzuki, Masayuki Yamamoto, Yuichi Ogino, Gotaro Shirakami, Akira Nishiyama

published 21 Apr 2026

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Distinct plasma cytokine and chemokine profiles in severe COVID-19 and septic shock

Se Ju Lee, Jaehoon Kim, Min Han, Jung Ah Lee, Yongseop Lee, Jung Ho Kim, Jin Young Ahn, Su Jin Jeong, Nam Su Ku, Joon-Sup Yeom, Jun Yong Choi

published 17 Apr 2026

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Coriander leaf essential oil as an immunomodulator: Enhancing NF-κB-driven RAW246.7 murine macrophages response to Candida albicans

Pratsanee Hiengrach, Pasinee Sangsiwarit, Waewta Kuwatjanakul, Kittipan Samerpitak, Pitchaya Luksanawilas

published 17 Apr 2026

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JMJD3 regulates the M2-like macrophage polarization and promotes the growth of breast cancer cells via STAT6/IRF4 axis

Juan Lyu, Enqin Wang, Shanmei Lyu, Ying Qian, Fen Ye, Xiuping Xu, Qing Wang, Tao Lu, Liangfeng Hu, Hongkun Xu, Lihong Zhang

published 09 Apr 2026

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Mapping the role of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its receptors in chronic kidney disease: A scoping review protocol

Hansani Niroshika, Harshi Weerakoon, Nalaka Herath, Kosala Weerakoon, Prasad Jayasooriya

published 07 Apr 2026

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FOXO1 transcription factor modulates airway epithelial responses to viral infection

Nadia M. Daniel, Ritu Mann-Nüttel, Nami Shrestha Palikhe, Joaquin López-Orozco, Tom Hobman, Paul Forsythe, Harissios Vliagoftis

published 03 Apr 2026

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Upregulation of interleukin-1β and interleukin-18 in traumatic brain injury patients and their potential as biomarkers

Saiqa Nazeer, Ghulam Murtaza

published 03 Apr 2026

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A phosphorous-based dendrimer targets mitochondria and normalizes the keratinocyte proliferation/differentiation balance to improve psoriasis

Emily Clement, Ranime Jebbawi, Abdelouahd Oukhrib, Hélène Labie, Maëlys Le Moal, Séverine Fruchon, Stéphanie Cassel, Anne-Marie Caminade, Cédric-Olivier Turrin, Muriel Blanzat, Michel Simon, Rémy Poupot

published 31 Mar 2026

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