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Innate immune system

Porphyromonas gingivalis outer membrane vesicles alter cortical neurons and Tau phosphorylation in the embryonic mouse brain

Adrienne J. Bradley, Lauren Mashburn-Warren, Lexie C. Blalock, Francesca Scarpetti, Christian L. Lauber

published 11 Mar 2025

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The effect of IL-1β inhibitor canakinumab (Ilaris®) on IL-6 production in human skeletal muscle cells

Anna Cordeiro-Santanach, Fiorella Morales, Maria del Carmen Parquet, Kitipong Uaesoontrachoon, Joyce Rowsell, Jordan Warford, Wilson Wu, Pia Elustondo, Eric P. Hoffman, Kanneboyina Nagaraju

published 06 Mar 2025

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Pharmacometabolomics in TB meningitis—Understanding the pharmacokinetic, metabolic, and immune factors associated with anti-TB drug concentrations in cerebrospinal fluid

Jeffrey M. Collins, Maia Kipiani, Yutong Jin, Ashish A. Sharma, Jeffrey A. Tomalka, Teona Avaliani, Mariam Gujabidze, Tinatin Bakuradze, Shorena Sabanadze, Zaza Avaliani, Henry M. Blumberg, David Benkeser, Dean P. Jones, Charles Peloquin, Russell R. Kempker

published 03 Mar 2025

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Study protocol: Exploratory trial of Forza™, an osmotin-based nutraceutical as adjuvant for the treatment of progressive multiple sclerosis

Viola Costa, Kenda Aluan, Irene Schiavetti, Caterina Bason, Tiziana Vigo, Elisa Leveraro, Corrado Cabona, Valeria Prada, Mauro Costagli, Vincenzo Daniele Boccia, Bruno Ruggiero, Giampaolo Brichetto, Marco Salvetti, Maria Pia Sormani, Gianluigi Mancardi, Matilde Inglese, Mario Alberto Battaglia

published 27 Feb 2025

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Stress-mediating inflammatory cytokine profiling reveals unique patterns in malaria and typhoid fever patients

MacDonald Bin Eric, Palmer Masumbe Netongo, Severin Donald Kamdem, Christine Nzuno, Ange Maxime Tchoutang, Tchoupe Kamoua Eric Berenger, Bongkiyung Donald Buri, Ngum Leslie Ngum, Jean Paul Chedjou, Akindeh Mbu Nji, Wilfred Fon Mbacham

published 27 Feb 2025

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Maternal vitamin D status in relation to cardiometabolic risk factors in children from the Norwegian Environmental Biobank

Anna Amberntsson, Linnea Bärebring, Anna Winkvist, Lauren Lissner, Anne Lise Brantsæter, Iris Erlund, Eleni Papadopoulou, Hanna Augustin

published 25 Feb 2025

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The alteration of uterine microbiota participated in the activation of the decidual inflammatory response in early spontaneous abortion

Ping Liu, Ge Chen, Shitong Zhao, Linglingli Kong, Xin Liao, Meng Cheng

published 24 Feb 2025

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Delayed hepatic response and impaired cytokine dynamics in aged mice following burn injury: Implications for elderly patient care

Israel Muro, Andrea C. Qualman, Kenneth Meza Monge, Akshay Pratap, Elizabeth J. Kovacs, Juan-Pablo Idrovo

published 24 Feb 2025

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Understanding the aliya pulsed electric field dose-response relationship: Implications for ablation size, thermal load, and immune response in an orthotopic murine breast cancer model

Ebtesam H. O. Nafie, Chiara Pastori, Rupsa Acharya, Rosa Kaviani, David Hunter, Waleed Shalaby, William S. Krimsky, Robert E. Neal II

published 13 Feb 2025

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Clinical status and cytokine profiles in patients with asthma or chronic obstructive pulmonary disease vaccinated against influenza

Mikhail Kostinov, Alexander Chuchalin, Anna Chebykina, Isabella Khrapunova, Alexander Cherdantsev, Irina Solov’eva, Nelli Akhmatova, Valentina Polishchuk, Nadezhda Kryukova, Aristitsa Kostinova, Anna Vlasenko, Marina Loktionova, Yvette Albahansa, Anna Shmit’ko, Lyudmila Shogenova

published 12 Feb 2025

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Nutraceutical COMP-4 confers protection against endothelial dysfunction through the eNOS/iNOS-NO-cGMP pathway

Monica G. Ferrini, Andrea Abraham, Revecca Millán, Leslie Graciano, Sriram V. Eleswarapu, Jacob Rajfer

published 06 Feb 2025

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Clinical, immune and genetic risk factors of malaria-associated acute kidney injury in Zambian children: A study protocol

Chisambo Mwaba, Sody Munsaka, David Mwakazanga, David Rutagwerae, Owen Ngalamika, Suzanna Mwanza, Mignon McCulloch, Evans Mpabalwani

published 06 Feb 2025

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Treatment with the CCR5 antagonist OB-002 reduces lung pathology, but does not prevent disease in a Syrian hamster model of SARS-CoV-2 infection

Bryce M. Warner, Robert Vendramelli, Amrit S. Boese, Jonathan Audet, Nikesh Tailor, Courtney Meilleur, Nathan Glowach, Marnie Willman, Thang Truong, Estella Moffat, Kevin Tierney, Beata Kosak, Irfan Dhanidina, Jarret Engstrom, Bozena Korczak, Ian McGowan, Carissa Embury-Hyatt, Darwyn Kobasa

published 05 Feb 2025

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