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Innate immune system

JMJD3 regulates the M2-like macrophage polarization and promotes the growth of breast cancer cells via STAT6/IRF4 axis

Juan Lyu, Enqin Wang, Shanmei Lyu, Ying Qian, Fen Ye, Xiuping Xu, Qing Wang, Tao Lu, Liangfeng Hu, Hongkun Xu, Lihong Zhang

published 09 Apr 2026

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Mapping the role of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its receptors in chronic kidney disease: A scoping review protocol

Hansani Niroshika, Harshi Weerakoon, Nalaka Herath, Kosala Weerakoon, Prasad Jayasooriya

published 07 Apr 2026

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FOXO1 transcription factor modulates airway epithelial responses to viral infection

Nadia M. Daniel, Ritu Mann-Nüttel, Nami Shrestha Palikhe, Joaquin López-Orozco, Tom Hobman, Paul Forsythe, Harissios Vliagoftis

published 03 Apr 2026

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Upregulation of interleukin-1β and interleukin-18 in traumatic brain injury patients and their potential as biomarkers

Saiqa Nazeer, Ghulam Murtaza

published 03 Apr 2026

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A phosphorous-based dendrimer targets mitochondria and normalizes the keratinocyte proliferation/differentiation balance to improve psoriasis

Emily Clement, Ranime Jebbawi, Abdelouahd Oukhrib, Hélène Labie, Maëlys Le Moal, Séverine Fruchon, Stéphanie Cassel, Anne-Marie Caminade, Cédric-Olivier Turrin, Muriel Blanzat, Michel Simon, Rémy Poupot

published 31 Mar 2026

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Intestinal barrier damage is associated with fine particulate matter (PM_2.5)-induced pathological aortic injury in mice

Xiangyong Hu, Ming Lei, Liping Du, Hongju Xiang, Jiaxin Hu, Jiaqi Yu, Zhixiong Liao, Yuyu Li

published 20 Mar 2026

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GBP2 promotes podocyte pyroptosis and contributes to the pathogenesis of pediatric lupus nephritis

Yu Sun, Jiahui Wei, Yanjun Zhao, Xingbo Jiang, Chao He, Xianhui Huang, Fengying Lei, Yuanhan Qin

published 19 Mar 2026

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Study protocol: Dental and periodontal characteristics of older adults in Atahualpa, Ecuador within the Atahualpa Project cohort

Marcelo Armijos Briones, Patricia Estefanía Ayala Aguirre, Pablo Lenin Benitez Sellan, Antonio Lanata-Flores, Oscar Marcillo-Toala, Denisse A. Rumbea, Robertino M. Mera, Oscar H. Del Brutto

published 19 Mar 2026

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Mode of action-specific and cause-specific retention of biologic and targeted synthetic disease-modifying antirheumatic drugs in anti-SS-A antibody-positive rheumatoid arthritis: The ANSWER cohort study

Kazuma Nishisaka, Takaichi Okano, Takumi Imai, Masanori Tsubosaka, Tomoyuki Kamenaga, Naoki Nakano, Shinya Hayashi, Wataru Yamamoto, Akira Onishi, Kosaku Murakami, Kohei Tsujimoto, Masao Katsushima, Ayaka Yoshikawa, Takuya Kotani, Hideki Amuro, Yonsu Son, Tetsu Itami, Yuji Nozaki, Yoko Nose, Mai Yamashita, Iku Shirasugi, Hirotaka Yamada, Keisuke Nishimura, Yo Ueda, Sho Sendo, Motomu Hashimoto, Ryosuke Kuroda, Jun Saegusa

published 18 Mar 2026

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Computational modeling-directed combination treatment with etanercept and mifepristone mitigates neuroinflammation in a mouse model of Gulf War Illness

Kimberly A. Kelly, Christopher M. Felton, Brenda K. Billig, Ali A. Yilmaz, James P. O’Callaghan, Travis J. A. Craddock, Gordon Broderick, Nancy Klimas, Lindsay T. Michalovicz

published 17 Mar 2026

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Combining lenalidomide with IL-2 family of cytokines enhances activating receptor and perforin/granzyme expression in NK cells

Alexandra Calescibetta, Robert Dalton, Nicole Fortenbery, Grace Ward, Sean Christiansen, Xianghong Chen, Pingyan Cheng, Tiffany Razabdouski, Annelise J. Glode, Nhan Tu, Thu Le Trinh, Jinghong Liu, Kenneth L. Wright, Sheng Wei, Erika Adriana Eksioglu

published 12 Mar 2026

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Examining the role of systemic inflammation as a mediator of the glycaemia-brain volume associations in women

Nasri Fatih, Nish Chaturvedi, Victoria Garfield, Carole H. Sudre, Richard J. Silverwood, David M. Cash, Ian B. Malone, Josephine Barnes, Marcus Richards, Jonathan M. Schott, Alun D. Hughes, Sarah-Naomi James

published 10 Mar 2026

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TLR9/MyD88/NF-κB signaling mediates mental stress-induced exacerbation of psoriasis through immune dysregulation in a mouse model

Qiuhe Song, Dongyang Li, Zhihao Yuan, Chaowen Zhang, Jianqiao Wang, Fangfang Liao, Pengfei Xu, Qipeng Xiao

published 06 Mar 2026

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