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Inflammasomes

GM-1111 reduces radiation-induced oral mucositis in mice by targeting pattern recognition receptor-mediated inflammatory signaling

Abigail Pulsipher, Justin R. Savage, [ ... ], Won Yong Lee

A role for the NLRC4 inflammasome in premature rupture of membrane

Jinming Zhu, Chunling Ma, [ ... ], Xiaomei Luan

Quercetin negatively regulates IL-1β production in Pseudomonas aeruginosa-infected human macrophages through the inhibition of MAPK/NLRP3 inflammasome pathways

Kasem Chanjitwiriya, Sittiruk Roytrakul, Duangkamol Kunthalert

Induced pluripotent stem cell-derived monocytic cell lines from a NOMID patient serve as a screening platform for modulating NLRP3 inflammasome activity

Ryosuke Seki, Akira Ohta, [ ... ], Megumu K. Saito

Lactic acid bacterium, Lactobacillus paracasei KW3110, suppresses inflammatory stress-induced caspase-1 activation by promoting interleukin-10 production in mouse and human immune cells

Takahiro Yamazaki, Konomi Ohshio, Miho Sugamata, Yuji Morita

NLRP3 inflammasome inhibition attenuates sepsis-induced platelet activation and prevents multi-organ injury in cecal-ligation puncture

Denise C. Cornelius, Olivia K. Travis, [ ... ], Jan M. Williams

Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis

Bernat Baeza-Raja, Andrew Goodyear, [ ... ], Karim Dabbagh

Anti-hyperglycemic activity of myricetin, through inhibition of DPP-4 and enhanced GLP-1 levels, is attenuated by co-ingestion with lectin-rich protein

Nanjaiah Lalitha, Bettadahalli Sadashivaiah, Talahalli Ravichandra Ramaprasad, Sridevi Annapurna Singh

Herpes simplex virus type 1 inflammasome activation in proinflammatory human macrophages is dependent on NLRP3, ASC, and caspase-1

Andrew H. Karaba, Alexis Figueroa, [ ... ], Andrea L. Cox

Influence of inflammasome NLRP3, and IL1B and IL2 gene polymorphisms in periodontitis susceptibility

Josiane Bazzo de Alencar, Joana Maira Valentini Zacarias, [ ... ], Ana Maria Sell

LTA1 and dmLT enterotoxin-based proteins activate antigen-presenting cells independent of PKA and despite distinct cell entry mechanisms

Eduardo Valli, Robin L. Baudier, Amanda J. Harriett, Elizabeth B. Norton

Inflammasome expression is higher in ovarian tumors than in normal ovary

Judith Luborsky, Animesh Barua, [ ... ], Seby L. Edassery

Antibiotics induced intestinal tight junction barrier dysfunction is associated with microbiota dysbiosis, activated NLRP3 inflammasome and autophagy

Yanhai Feng, Yalan Huang, [ ... ], Fengjun Wang

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