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Immunotherapy

Development of a prostate cancer biochemical recurrence risk signature using machine learning and motor protein-related genes

Weixing Wang, Guohai Xie, Zhonggao Wu

published 16 Sep 2025

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A phosphoramidate modification of FUDR, NUC-3373, causes DNA damage and DAMPs release from colorectal cancer cells, potentiating lymphocyte-induced cell death

Oliver J. Read, Jennifer Bré, Ying Zhang, Peter Mullen, Mustafa Elshani, David J. Harrison

published 16 Sep 2025

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Assessing the real-world safety of docetaxel for non-small cell lung cancer: Insights from a comprehensive analysis of FAERS data

Lei Wang, Hui Zhao, Kunpeng Yang, Zhe Wang, Chenglun Cai, Peiyun Lv, Bao Wang

published 12 Sep 2025

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Optimizing canine T cell activation, expansion, and transduction

Treyvon W. Davis, Jennifer C. Holmes, Arissa He, Paul R. Hess, Christopher L. Mariani, Yevgeny Brudno

published 11 Sep 2025

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Dynamic of competitive Lotka-Volterra model for tumor-host systems under constant or periodic perturbation: Implications for the therapy of cancer

Rolando Placeres Jimenez, Luis E. Bergues Cabrales, Juan I. Montijano

published 25 Aug 2025

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A multi-omics atlas of CAF subtypes reveals apCAF–M2 macrophage interactions driving immune resistance in glioma

Yubo Ren, Dengfeng Lu, Fei Wang, Zixuan Wang, Jinfeng Li, Run Huang, Yue Lu, Aojie Duan, Renjie Shou, Jiangang Liu, Zhouqing Chen, Zhong Wang, Xiaoou Sun

published 11 Aug 2025

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Prevalence and clinicopathological characteristics of breast cancer patients with brain metastases in Ghana: A single-center cross-sectional study

Joseph Daniels, Kofi Adesi Kyei, Ronald Walubo, Andrew Yaw Nyantakyi, Edwina Ayaaba Ayabilah, Judith Naa Odey Tackie

published 08 Aug 2025

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Contemporaneous symptom networks for multidimensional symptom experience in lung cancer survivors of immunotherapy: A network analysis

Hang Gao, Xiaoxue Wen, Xiaoli Sun, Yuwei Liu, Jianwen Hou, Danwen Zheng, Hejia Chen, Lingfang Ma, Yufang Zhou, Xinyan Yu

published 10 Jul 2025

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In silico identification of promising PD-L1 inhibitors from selected indian medicinal plants for treatment of triple negative breast cancer

Sk. Faisal Ahmed, Md. Shohel Hossain, Amalesh Mondal, Musab Shahariar, Shormila Akter Sumya, Nahid Sultan Rizu, Lamia Hasan Joarder Barsha

published 10 Jul 2025

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Serum zinc as a biomarker to predict the efficacy of immune checkpoint inhibitors in cancers

Jingliang Wang, Weihao Wang, Bin Liu, Rui Zhao, Jing Zhao, Fengxian Jiang, Wei Xu, Zhizhao Zhang, Pancen Ran, Yang Shu, Yahui Wang, Liying Pan, Lei Liu, Fang Luan, Guobin Fu

published 03 Jul 2025

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Tumor-associated macrophage-based predictive and prognostic model for hepatocellular carcinoma

Changquan Shang, Tiancong He, Yi Zhang

published 02 Jul 2025

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Contrast-enhanced ultrasound with VEGFR2-targeted microbubbles for monitoring combined anti-PD-L1/anti-CTLA-4 immunotherapy effects in a murine melanoma model with immunohistochemical validation

Felix L. Herr, Melissa J. Antons, Larissa V. Blume, Heidrun Hirner-Eppeneder, Sandra Kloiber-Langhorst, Amra Cimic, Jennifer Stueckl, Isabelle Tardy, Tanja Burkard, Jens Ricke, Wolfgang G. Kunz, Dirk-Andre Clevert, Maurice M. Heimer, Clemens C. Cyran

published 01 Jul 2025

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Hepatitis B virus X protein (HBx)-mediated immune modulation and prognostic model development in hepatocellular carcinoma

Jianhua Zhong, Yuetong Li, Yang Liu, Jie Qiao, Yiling Wu, Xinyi Kong, Miao Qi, Yiqi Lin, Yaqi Yao, Ying Jin, Changlong Bi, Aixia Zhai

published 27 Jun 2025

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