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Immune system

IMD-4690, a Novel Specific Inhibitor for Plasminogen Activator Inhibitor-1, Reduces Allergic Airway Remodeling in a Mouse Model of Chronic Asthma via Regulating Angiogenesis and Remodeling-Related Mediators

Toshifumi Tezuka, Hirohisa Ogawa, Masahiko Azuma, Hisatsugu Goto, Hisanori Uehara, Yoshinori Aono, Masaki Hanibuchi, Yoichi Yamaguchi, Tomoyuki Fujikawa, Akiko Itai, Yasuhiko Nishioka

published 18 Mar 2015

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Aging-Related Systemic Manifestations in COPD Patients and Cigarette Smokers

Laurent Boyer, Christos Chouaïd, Sylvie Bastuji-Garin, Elisabeth Marcos, Laurent Margarit, Philippe Le Corvoisier, Laetitia Vervoitte, Leila Hamidou, Lamia Frih, Etienne Audureau, Ala Covali-Noroc, Pascal Andujar, Zakaria Saakashvili, Anne Lino, Bijan Ghaleh, Sophie Hue, Geneviève Derumeaux, Bruno Housset, Jean-Luc Dubois-Randé, Jorge Boczkowski, Bernard Maitre, Serge Adnot

published 18 Mar 2015

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Obesity Impairs γδ T Cell Homeostasis and Antiviral Function in Humans

Anne E. Costanzo, Kristen R. Taylor, Shelley Dutt, Peggy P. Han, Ken Fujioka, Julie M. Jameson

published 18 Mar 2015

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Recognition of Neisseria meningitidis by the Long Pentraxin PTX3 and Its Role as an Endogenous Adjuvant

Barbara Bottazzi, Laura Santini, Silvana Savino, Marzia M. Giuliani, Ana I. Dueñas Díez, Giuseppe Mancuso, Concetta Beninati, Marina Sironi, Sonia Valentino, Livija Deban, Cecilia Garlanda, Giuseppe Teti, Mariagrazia Pizza, Rino Rappuoli, Alberto Mantovani

published 18 Mar 2015

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A Single Naturally Occurring 2’-O-Methylation Converts a TLR7- and TLR8-Activating RNA into a TLR8-Specific Ligand

Stephanie Jung, Tina von Thülen, Viktoria Laukemper, Stephanie Pigisch, Doris Hangel, Hermann Wagner, Andreas Kaufmann, Stefan Bauer

published 18 Mar 2015

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Combined Antigen-Specific Interferon-γ and Interleukin-2 Release Assay (FluoroSpot) for the Diagnosis of Mycobacterium tuberculosis Infection

Dumitru Chesov, Christoph Lange, Franziska Daduna, Valeriu Crudu, Rosemarie Preyer, Martin Ernst, Barbara Kalsdorf

published 18 Mar 2015

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Endothelial Nitric Oxide Synthase Deficient Mice Are Protected from Lipopolysaccharide Induced Acute Lung Injury

Christine M. Gross, Ruslan Rafikov, Sanjiv Kumar, Saurabh Aggarwal, P. Benson Ham III, Mary Louise Meadows, Mary Cherian-Shaw, Archana Kangath, Supriya Sridhar, Rudolf Lucas, Stephen M. Black

published 18 Mar 2015

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Involvement of Neutrophil Hyporesponse and the Role of Toll-Like Receptors in Human Immunodeficiency Virus 1 Protection

Juan C. Hernandez, Diana M. Giraldo, Stephane Paul, Silvio Urcuqui-Inchima

published 18 Mar 2015

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Myocardial Mitochondrial and Contractile Function Are Preserved in Mice Lacking Adiponectin

Martin Braun, Niko Hettinger, Christoph Koentges, Katharina Pfeil, Maria C. Cimolai, Michael M. Hoffmann, Moritz Osterholt, Torsten Doenst, Christoph Bode, Heiko Bugger

published 18 Mar 2015

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Comparative Genomic Analysis of Buffalo (Bubalus bubalis) NOD1 and NOD2 Receptors and Their Functional Role in In-Vitro Cellular Immune Response

Biswajit Brahma, Sushil Kumar, Bidhan Chandra De, Purusottam Mishra, Mahesh Chandra Patra, Deepak Gaur, Meenu Chopra, Devika Gautam, Sourav Mahanty, Hrudananda Malik, Dhruba Malakar, Tirtha Kumar Datta, Sachinandan De

published 18 Mar 2015

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Mechanisms of Immunity in Post-Exposure Vaccination against Ebola Virus Infection

Steven B. Bradfute, Scott M. Anthony, Kelly S. Stuthman, Natarajan Ayithan, Prafullakumar Tailor, Carl I. Shaia, Mike Bray, Keiko Ozato, Sina Bavari

published 18 Mar 2015

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Design and Evaluation of Optimized Artificial HIV-1 Poly-T Cell-Epitope Immunogens

Alena Reguzova, Denis Antonets, Larisa Karpenko, Alexander Ilyichev, Rinat Maksyutov, Sergei Bazhan

published 18 Mar 2015

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Upregulation of Glycolytic Enzymes, Mitochondrial Dysfunction and Increased Cytotoxicity in Glial Cells Treated with Alzheimer’s Disease Plasma

Tharusha Jayasena, Anne Poljak, Nady Braidy, George Smythe, Mark Raftery, Mark Hill, Henry Brodaty, Julian Trollor, Nicole Kochan, Perminder Sachdev

published 18 Mar 2015

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