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Immune system

Disruption of epidermal growth factor receptor signaling and cytoskeletal dynamics by mebendazole and gefitinib synergistically impairs paracrine cytokine signaling in non-small cell lung cancer and triple-negative breast cancer Cell lines

Mohamed El-Tanani, Shakta Mani Satyam, Syed Arman Rabbani, Yahia El-Tanani, Mark Sutherland, Frezah Muhana

published 16 Dec 2025

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High-protein diets reduce plasma pro-inflammatory cytokines following lipopolysaccharide challenge in Swiss Albino mice

Hellen W. Kinyi, Charles Kato Drago, Lucy Ochola, Gertrude N. Kiwanuka

published 15 Dec 2025

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The effects of 12 weeks of chiropractic spinal adjustments on physiological biomarkers in adults: A pragmatic randomized controlled trial

Imran Amjad, Imran Khan Niazi, Nitika Kumari, Usman Ghani, Usman Rashid, Felipe Coutinho Kullmann Duarte, Federico Fortuna, Silvia Iglesias, Diego Gonzalez, Alex Sumich, Bibiana Fabre, Kelly Holt, Heidi Haavik

published 11 Dec 2025

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Anti-arthritic and endothelial protective effects of Derris scandens extract in adjuvant-induced arthritis in rats

Nattiya Chaichamnong, Corine Girard, Maude Tournier, Francis Bonnefoy, Kornkanok Ingkaninan, Céline Demougeot, Perle Totoson

published 11 Dec 2025

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Inflammatory cytokines promote interferon regulatory factor (IRF) transcriptional activity in human pulmonary epithelial cells through the induction of IRF1 by nuclear factor-κB

Amandah Necker-Brown, Mahmoud M. Mostafa, Andrei Georgescu, Andrew J. Thorne, Priyanka Chandramohan, Cora Kooi, Keerthana Kalyanaraman, Alex Gao, Akanksha Bansal, Sarah K. Sasse, Anthony N. Gerber, Richard Leigh, Robert Newton

published 08 Dec 2025

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Co-regulation of microglial subgroups in Alzheimer’s amyloid pathology: Implications for diagnosis and drug development

Yu Zhou, Yukuan Huang, Yangchang Fan, Feng Xue

published 05 Dec 2025

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Control of quiescence and activation of human muscle stem cells by cytokines

Katharine Striedinger, Emilie Barruet, Elena Atamaniauc, Karla Linquist, Chris Knott, Andrew Brack, Jason H. Pomerantz

published 05 Dec 2025

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Characterization of p53 p.T253I as a pathogenic mutation underlying Li-Fraumeni Syndrome

Nathaniel C. Holcomb, Amanda M. Harrington, Hong Pu, Berina Halilovic, Nathan R. Shelman, Shulin Zhang, Catherine Sears, Terra Armstrong, Brent Shelton, Lauren Corum, John A. D'Orazio

published 05 Dec 2025

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Proinflammatory gene and protein expression alterations in human limbal aniridia fibroblasts

Julia Sarah Alexandra Zimmermann, Simon Trusen, Fabian Norbert Fries, Zhen Li, Ning Chai, Berthold Seitz, Shweta Suiwal, Maryam Amini, Nóra Szentmáry, Tanja Stachon

published 04 Dec 2025

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Immune transcriptomic changes in Australian Gulf War veterans

Natalie Eaton-Fitch, Etianne Martini Sasso, Sonya Marshall-Gradisnik

published 03 Dec 2025

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Evogliptin prevents ceramide-induced pyroptosis during calcification via modulation of NLRP3/GSDM-D mediated pathway in Vascular Smooth Muscle Cells

Razia Rashid Rahil, Salman Shamas, Nissar Ahmad Wani, Neha Nanda, Sheikh Fayaz Ahmad, Sabry Mohamed Attia, Abid Hamid, Mohammad Afzal Zargar, Owais Mohmad Bhat

published 03 Dec 2025

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Is low birth weight associated with lower adiponectin levels? - A systematic review and meta-analysis

Afnan Sabah Alhakeem, Aleyna Hasturk, Trine Witzner Hessel Lawaetz, Tue Helms Andersen, Charlotte Brøns, Allan Arthur Vaag

published 02 Dec 2025

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The role of amino bisphosphonates zoledronate and alendronate in shaping immunomodulatory profile and angiogenic potential of human periodontal ligament stem cells

Jessica Bria, Emanuela Chiarella, Jessica Sovereto, Francesco Baudi, Marta Greco, Daniela Patrizia Foti, Amerigo Giudice, Anna Di Vito

published 01 Dec 2025

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