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Immune system

Toll-like receptor 1/2 activation reduces immunoglobulin free light chain production by multiple myeloma cells in the context of bone marrow stromal cells and fibronectin

Jahan Abdi, Frank Redegeld

published 28 Jan 2025

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The cellular response of lipopolysaccharide-induced inflammation in keratoconus human corneal fibroblasts to RB-PDT: Insights into cytokines, chemokines and related signaling pathways

Ning Chai, Tanja Stachon, Sabrina Häcker, Tim Berger, Zhen Li, Maryam Amini, Shweta Suiwal, Berthold Seitz, Achim Langenbucher, Nóra Szentmáry

published 27 Jan 2025

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Activation of S1PR2 on macrophages and the hepatocyte S1PR2/RhoA/ROCK1/MLC2 pathway in vanishing bile duct syndrome

Aya Miyagawa-Hayashino, Tetsuya Imura, Toshiaki Takezawa, Maki Hirai, Saya Shibata, Hiroshi Ogi, Takahiro Tsujikawa, Eiichi Konishi

published 24 Jan 2025

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Secondary metabolites of Alternaria alternate appraisal of their SARS-CoV-2 inhibitory and anti-inflammatory potentials

Fatma A. Moharram, Reham R. Ibrahim, Shahenda Mahgoub, Mohamed S. Abdel-Aziz, Ahmed M. Said, Hui-Chi Huang, Lo-Yun Chen, Kuei-Hung Lai, Nashwa Hashad, Mohamed S. Mady

published 24 Jan 2025

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Notch dimerization provides robustness against environmental insults and is required for vascular integrity

Kristina Preusse, Kim Cochran, Quanhui Dai, Raphael Kopan

published 24 Jan 2025

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Toll-like receptor 2/6-stimulated HMC-1 mast cells promote keratinocyte migration in wound healing

Jiyun Kwon, Kyung-Ah Cho, So-Youn Woo

published 17 Jan 2025

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Oral administration of Limosilactobacillus reuteri VHProbi^® M07 alleviates ovalbumin-induced allergic asthma in mice

Guoqing Meng, Hongchang Cui, Congrui Feng, Chaoqun Guo, Lei Song, Zhi Duan

published 16 Jan 2025

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RORγt inverse agonists demonstrating a margin between inhibition of IL-17A and thymocyte apoptosis

Mia Collins, Rikard Pehrson, Hanna Grindebacke, Agnes Leffler, Marie Ramnegård, Helena Rannikmäe, Nina Krutrök, Linda Yrlid, Charlotte Pollard, Ian Dainty, Frank Narjes, Stefan von Berg, Antonio Llinas, Anna Malmberg, Jane McPheat, Eva Hansson, Elisabeth Bäck, Jenny Bernström, Thomas G. Hansson, David Keeling, Johan Jirholt

published 16 Jan 2025

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N-terminomics profiling of host proteins targeted by excretory-secretory proteases of the nematode Angiostrongylus vasorum identifies points of interaction with canine coagulation and complement cascade

Nina Germitsch, Tobias Kockmann, Manuela Schnyder, Lucienne Tritten

published 15 Jan 2025

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Does curcumin supplementation affect inflammation, blood count and serum brain-derived neurotropic factor concentration in amateur long-distance runners?

Sebastian Bańkowski, Ziemowit Bronisław Wójcik, Małgorzata Grabara, Dariusz Ozner, Tomasz Pałka, Agata Stanek, Ewa Sadowska-Krępa

published 14 Jan 2025

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Plant-derived Pembrolizumab in conjugation with IL-15Rα-IL-15 complex shows effective anti-tumor activity

Kaewta Rattanapisit, Pipob Suwanchaikasem, Christine Joy I. Bulaon, Shiying Guo, Waranyoo Phoolcharoen

published 14 Jan 2025

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Bacillus coagulans alleviates hepatic injury caused by Klebsiella pneumoniae in rabbits

Xiaoguang Chen, Wenjuan Wei, Fan Yang, Jianing Wang, Qiongxia Lv, Yumei Liu, Ziqiang Zhang

published 10 Jan 2025

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Modifications to rhesus macaque TCR constant regions improve TCR cell surface expression

Lori V. Coren, Matthew T. Trivett, Jorden L. Welker, James A. Thomas, Robert J. Gorelick, Emek Kose, Taina T. Immonen, Kelli Czarra, Christine M. Fennessey, Charles M. Trubey, Jeffrey D. Lifson, Adrienne E. Swanstrom

published 09 Jan 2025

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