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Immune system

Benznidazole therapy improves pressure overload and cardiac electrical profile in an experimental model of Angiotensin II infusion-induced hypertension: Mechanistic insights

Paula da Silva Pinheiro, Glaucia Vilar-Pereira, Leda Castaño-Barrios, Isalira Peroba Rezende Ramos, Yasmin Pedra-Rezende, Luiza Dantas-Pereira, Rubem Figueiredo Sadok Menna-Barreto, Daniel Gibaldi, Hilton Antônio Mata-Santos, Joseli Lannes-Vieira

published 27 Jan 2026

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Cardiosphere-derived cells in the primary prevention of sepsis-induced acute lung injury in pigs

James Frederick Dawkins, Asma Nawaz, Lizbeth Sanchez, Ralf Sulague, Aiyana Verfaillie, Juan Cardenas, Eugenio Cingolani, Michael Lewis, Eduardo Marbán

published 27 Jan 2026

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Tunicates have a complex, highly dynamic TNF superfamily

Ignacio Marín

published 27 Jan 2026

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Dupilumab attenuates the expression of TSLP and IL-8 induced by dsRNA and IL-4/IL-13 co-stimulation in human small airway epithelial cells

Aditya Sri Listyoko, Ryota Okazaki, Tomoya Harada, Genki Inui, Hiroki Kohno, Miyu Nishigami, Miki Takata, Masato Morita, Akira Yamasaki

published 23 Jan 2026

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Real-world study: Assessing the impact of hemolysis on 48 biochemical and immunological analytes through big data analysis and its feasibility validation

Chaochao Ma, Xiaoqi Li, Wei Luo, Lian Hou, Dandan Sun, Li Liu, Xin Liu, Ying Zhang, Jingrong Xu, Ling Qiu, Liangyu Xia

published 23 Jan 2026

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Formononetin ameliorates SP-induced urticaria in mice via suppressing TAK1/MAK signaling pathway

Yan Wu, Chunyu Li

published 23 Jan 2026

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Dynamical modeling of TNF-α, IL-6, and IL-10 interactions in stroke-induced inflammation

Fozia Ali M. Arishi, Azmin Sham Rambely, Fatimah Abdul Razak

published 20 Jan 2026

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Oxyphenbutazone improves memory and learning impairments in LPS-induced neurotoxicity via modulating TGF-β/NF-κB/IκB-α pathways: In silico and in vivo study

Khalid Saad Alharbi, Muhammad Afzal, Sattam Khulaif Alenezi, Reem ALQahtani, Tariq G. Alsahli, Faisal Imam, Imran Kazmi

published 20 Jan 2026

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Association of vaginal IL-4, IL-6, IL-8, IL-17, IFN-γ, and dietary intake with IBD status and vaginal microbiota in pregnant individuals

Daniela Vargas-Robles, Yan Rou Yap, Biplab Singha, Joyce Tien, Mallika Purandare, Mayra Rojas-Correa, Camilla Madziar, Mellissa Picker, Tina Dumont, Heidi K. Leftwich, Christine F. Frisard, Doyle V. Ward, Inga Peter, Barbara Olendzki, Ana Maldonado-Contreras

published 14 Jan 2026

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A TGFB2/TNF-induced in vitro model of proliferative vitreoretinopathy (PVR) using ARPE-19 cells confirms nicotinamide as an inhibitor of EMT and VEGFA secretion

Yuqing Huang, Roland Meister, Migle Lindziute, Maximilian Binter, Jan Tode, Carsten Framme, Heiko Fuchs

published 13 Jan 2026

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Lactiplantibacillus plantarum Membrane Vesicles (MVs) exhibit immunomodulatory and bactericidal effects against Escherichia coli and Salmonella Typhimurium

Cristal Dafne Lonngi Sosa, Francisco Rodolfo González Díaz, Hugo Ramírez Álvarez, Alejandro Vargas Ruíz, José Luis Muciño Hernández, Rosa Isabel Higuera Piedrahita, Héctor Alejandro de la Cruz Cruz, Marisela Leal Hernández, Gerardo Ramírez-Rico, Jorge Alfredo Cuéllar Ordaz, Cynthia González Ruíz

published 07 Jan 2026

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Identification of new triazoloquinoxaline amine derivatives with potent modulatory effects against Toll-like receptor 7 through pharmacophore-based virtual screening and molecular docking approaches

Nasrin Saberi Harooni, Mohammad Reza Naimi-Jamal, Sajjad Gharaghani, Asal Katebi, Soheila Ajdary, Azar Tahghighi

published 29 Dec 2025

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Lack of association between loneliness, social isolation and inflammation in people living with HIV aged ≥50 years: Results from the sub-study “No One Alone-Gesida Study”

Jose-Ramon Blanco, Helena Albendin-Iglesias, Eugenia Negredo-Puigmal, Ana Mª Barrios-Blandino, Cristina Tomás-Jimenez, Isabel Sanjoaquin-Conde, María Saumoy, Verónica Pérez-Esquerdo, Inmaculada Gonzalez-Cuello, Ana María López-Lirola, María José Galindo, Noemí Cabello-Clotet, Jesica Abadía Otero, Dolores Merino-Muñoz, Joanna Cano-Smith, Magdalena Muelas-Fernandez, Javier De La Torre, Alicia González-Baeza, Lourdes Romero, Antonio Ocampo, Rafael Torres, Carmen Hidalgo, Herminia Esteban, Maria Angeles Fernandes-López, Jordi Puig, Lucio Garcia Fraile, Enrique Bernal Morell, Laura Perez-Martinez, Marta De Miguel Montero, Inma Jarrin, Julian Olalla, THE GESIDA 12021 STUDY GROUP

published 17 Dec 2025

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