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Immune system

TRPV4 inhibition attenuates stretch-induced inflammatory cellular responses and lung barrier dysfunction during mechanical ventilation

N. Pairet, S. Mang, G. Fois, M. Keck, M. Kühnbach, J. Gindele, M. Frick, P. Dietl, D. J. Lamb

published 17 Apr 2018

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Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation

Joanne K. Gardner, Scott M. J. Cornwall, Arthur W. Musk, John Alvarez, Cyril D. S. Mamotte, Connie Jackaman, Anna K. Nowak, Delia J. Nelson

published 13 Apr 2018

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Design and preclinical characterization of ALXN1210: A novel anti-C5 antibody with extended duration of action

Douglas Sheridan, Zhao-Xue Yu, Yuchun Zhang, Rekha Patel, Fang Sun, Melissa A. Lasaro, Keith Bouchard, Bruce Andrien, Andre Marozsan, Yi Wang, Paul Tamburini

published 12 Apr 2018

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A low dose lipid infusion is sufficient to induce insulin resistance and a pro-inflammatory response in human subjects

Hanyu Liang, Helen Lum, Andrea Alvarez, Jose de Jesus Garduno-Garcia, Benjamin J. Daniel, Nicolas Musi

published 12 Apr 2018

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Strychnos pseudoquina modulates the morphological reorganization of the scar tissue of second intention cutaneous wounds in rats

Mariáurea Matias Sarandy, Lyvia Lopes Miranda, Luciana Schulthais Altoé, Rômulo Dias Novaes, Virgínia Vinha Zanuncio, João Paulo Viana Leite, Reggiani Vilela Gonçalves

published 12 Apr 2018

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Serum interleukin-6 and tumor necrosis factor-α are associated with early graft regeneration after living donor liver transplantation

Min Suk Chae, Kwang Uck Moon, Hyun Sik Chung, Chul Soo Park, Jaemin Lee, Jong Ho Choi, Sang Hyun Hong

published 12 Apr 2018

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Bronchoalveolar lavage (BAL) cells in idiopathic pulmonary fibrosis express a complex pro-inflammatory, pro-repair, angiogenic activation pattern, likely associated with macrophage iron accumulation

Jungnam Lee, Ivan Arisi, Ermanno Puxeddu, Lazarus K. Mramba, Massimo Amicosante, Carmen M. Swaisgood, Marco Pallante, Mark L. Brantly, C. Magnus Sköld, Cesare Saltini

published 12 Apr 2018

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Dimeric IgG complexes from IVIg are incapable of inducing in vitro neutrophil degranulation or complement activation

Iwan Kustiawan, Ninotska I. L. Derksen, Theresa Guhr, Simone Kruithof, Wim Jiskoot, Gestur Vidarsson, Theo Rispens

published 10 Apr 2018

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Leptospiral flagellar sheath protein FcpA interacts with FlaA2 and FlaB1 in Leptospira biflexa

Yuya Sasaki, Akihiro Kawamoto, Hajime Tahara, Kie Kasuga, Ryoichi Sato, Makoto Ohnishi, Shuichi Nakamura, Nobuo Koizumi

published 10 Apr 2018

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Acute glomerulonephritis with large confluent IgA-dominant deposits associated with liver cirrhosis

Jessica Hemminger, Vidya Arole, Isabelle Ayoub, Sergey V. Brodsky, Tibor Nadasdy, Anjali A. Satoskar

published 10 Apr 2018

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Toll-like receptor 3 (TLR3) promotes the resolution of Chlamydia muridarum genital tract infection in congenic C57BL/6N mice

Sebastian E. Carrasco, Sishun Hu, Denise M. Imai, Ramesh Kumar, George E. Sandusky, X. Frank Yang, Wilbert A. Derbigny

published 06 Apr 2018

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Hypocomplementemia is associated with worse renal survival in ANCA-positive granulomatosis with polyangiitis and microscopic polyangiitis

Samuel Deshayes, Achille Aouba, Kathy Khoy, Delphine Mariotte, Thierry Lobbedez, Nicolas Martin Silva

published 05 Apr 2018

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Rotavirus intestinal infection induces an oral mucosa cytokine response

José Gómez-Rial, María José Curras-Tuala, Irene Rivero-Calle, Carmen Rodríguez-Tenreiro, Lorenzo Redondo-Collazo, Alberto Gómez-Carballa, Jacobo Pardo-Seco, Antonio Salas, Federico Martinón-Torres

published 05 Apr 2018

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