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Hydroxylation

Identification of the Lomofungin Biosynthesis Gene Cluster and Associated Flavin-Dependent Monooxygenase Gene in Streptomyces lomondensis S015

Chunxiao Zhang, Chaolan Sheng, [ ... ], Xuehong Zhang

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

Mun Chiang Chan, Onur Atasoylu, [ ... ], Christopher J. Schofield

Antioxidant Activity of Caffeic Acid against Iron-Induced Free Radical Generation—A Chemical Approach

Thiago C. Genaro-Mattos, Ângelo Q. Maurício, [ ... ], Marcelo Hermes-Lima

Myeloid Translocation Gene-16 Co-Repressor Promotes Degradation of Hypoxia-Inducible Factor 1

Parveen Kumar, Urban Gullberg, Inge Olsson, Ram Ajore

The Toluene o-Xylene Monooxygenase Enzymatic Activity for the Biosynthesis of Aromatic Antioxidants

Giuliana Donadio, Carmen Sarcinelli, [ ... ], Viviana Izzo

In Vitro and In Vivo Metabolism and Inhibitory Activities of Vasicine, a Potent Acetylcholinesterase and Butyrylcholinesterase Inhibitor

Wei Liu, Xiaoyuan Shi, [ ... ], Changhong Wang

Prediction of Overall In Vitro Microsomal Stability of Drug Candidates Based on Molecular Modeling and Support Vector Machines. Case Study of Novel Arylpiperazines Derivatives

Szymon Ulenberg, Mariusz Belka, [ ... ], Tomasz Bączek

YCZ-18 Is a New Brassinosteroid Biosynthesis Inhibitor

Keimei Oh, Tadashi Matsumoto, [ ... ], Takeshi Nakano

Intermediary Metabolite Precursor Dimethyl-2-Ketoglutarate Stabilizes Hypoxia-Inducible Factor-1α by Inhibiting Prolyl-4-Hydroxylase PHD2

Peifeng Hou, Ching-Ying Kuo, [ ... ], Qiang Chen

Dihydroflavonol 4-Reductase Genes Encode Enzymes with Contrasting Substrate Specificity and Show Divergent Gene Expression Profiles in Fragaria Species

Silvija Miosic, Jana Thill, [ ... ], Heidi Halbwirth

Identification and Characterization of a New Erythromycin Biosynthetic Gene Cluster in Actinopolyspora erythraea YIM90600, a Novel Erythronolide-Producing Halophilic Actinomycete Isolated from Salt Field

Dandan Chen, Junyin Feng, [ ... ], Zhinan Xu

Structure-Function Analysis of Porcine Cytochrome P450 3A29 in the Hydroxylation of T-2 Toxin as Revealed by Docking and Mutagenesis Studies

Guyue Cheng, Changcun Liu, [ ... ], Zonghui Yuan

A Systems Biology-Based Approach to Uncovering the Molecular Mechanisms Underlying the Effects of Dragon's Blood Tablet in Colitis, Involving the Integration of Chemical Analysis, ADME Prediction, and Network Pharmacology

Haiyu Xu, Yanqiong Zhang, [ ... ], Luqi Huang

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