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Human genetics

Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study

Patrick Linsel-Nitschke, Anika Götz, Jeanette Erdmann, Ingrid Braenne, Peter Braund, Christian Hengstenberg, Klaus Stark, Marcus Fischer, Stefan Schreiber, Nour Eddine El Mokhtari, Arne Schaefer, Jürgen Schrezenmeier, Diana Rubin, Anke Hinney, Thomas Reinehr, Christian Roth, Jan Ortlepp, Peter Hanrath, Alistair S. Hall, Massimo Mangino, Wolfgang Lieb, Claudia Lamina, Iris M. Heid, Angela Doering, Christian Gieger, Annette Peters, Thomas Meitinger, H.-Erich Wichmann, Inke R. König, Andreas Ziegler, Florian Kronenberg, Nilesh J. Samani, Heribert Schunkert, for the Wellcome Trust Case Control Consortium (WTCCC) and the Cardiogenics Consortium

published 20 Aug 2008

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Genes to Diseases (G2D) Computational Method to Identify Asthma Candidate Genes

Karine Tremblay, Mathieu Lemire, Camille Potvin, Alexandre Tremblay, Gary M. Hunninghake, Benjamin A. Raby, Thomas J. Hudson, Carolina Perez-Iratxeta, Miguel A. Andrade-Navarro, Catherine Laprise

published 06 Aug 2008

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Non-Replication of Genome-Wide Based Associations between Common Variants in INSIG2 and PFKP and Obesity in Studies of 18,014 Danes

Camilla H. Andreasen, Mette S. Mogensen, Knut Borch-Johnsen, Annelli Sandbæk, Torsten Lauritzen, Thorkild I. A. Sørensen, Lars Hansen, Katrine Almind, Torben Jørgensen, Oluf Pedersen, Torben Hansen

published 06 Aug 2008

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Neither Replication nor Simulation Supports a Role for the Axon Guidance Pathway in the Genetics of Parkinson's Disease

Yonghong Li, Charles Rowland, Georgia Xiromerisiou, Robert J. Lagier, Steven J. Schrodi, Efthimios Dradiotis, David Ross, Nam Bui, Joseph Catanese, Konstantinos Aggelakis, Andrew Grupe, Georgios Hadjigeorgiou

published 16 Jul 2008

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Population Substructure and Control Selection in Genome-Wide Association Studies

Kai Yu, Zhaoming Wang, Qizhai Li, Sholom Wacholder, David J. Hunter, Robert N. Hoover, Stephen Chanock, Gilles Thomas

published 02 Jul 2008

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Density of Common Complex Ocular Traits in the Aging Eye: Analysis of Secondary Traits in Genome-Wide Association Studies

Albert O. Edwards, Sung J. Lee, Brooke L. Fridley, Nirubol Tosakulwong

published 25 Jun 2008

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Mitochondrial DNA Haplogroup Analysis Reveals no Association between the Common Genetic Lineages and Prostate Cancer in the Korean Population

Wook Kim, Tag-Keun Yoo, Dong-Jik Shin, Hyun-Wook Rho, Han-Jun Jin, Eun-Tak Kim, Yoon-Sun Bae

published 21 May 2008

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Hepatitis C Virus Diversity and Evolution in the Full Open-Reading Frame during Antiviral Therapy

Nathan A. Cannon, Maureen J. Donlin, Xiaofeng Fan, Rajeev Aurora, John E. Tavis, for the Virahep-C Study Group

published 07 May 2008

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Post Genome-Wide Association Studies of Novel Genes Associated with Type 2 Diabetes Show Gene-Gene Interaction and High Predictive Value

Stéphane Cauchi, David Meyre, Emmanuelle Durand, Christine Proença, Michel Marre, Samy Hadjadj, Hélène Choquet, Franck De Graeve, Stefan Gaget, Frederic Allegaert, Jérôme Delplanque, Marshall Alan Permutt, Jon Wasson, Ilana Blech, Guillaume Charpentier, Beverley Balkau, Anne-Claire Vergnaud, Sébastien Czernichow, Wolfgang Patsch, Mohamed Chikri, Benjamin Glaser, Robert Sladek, Philippe Froguel

published 07 May 2008

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Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study

Klaus Stark, Wibke Reinhard, Katharina Neureuther, Silke Wiedmann, Kamil Sedlacek, Andrea Baessler, Marcus Fischer, Stefan Weber, Bernhard Kaess, Jeanette Erdmann, Heribert Schunkert, Christian Hengstenberg

published 09 Apr 2008

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Association Analysis of the FTO Gene with Obesity in Children of Caucasian and African Ancestry Reveals a Common Tagging SNP

Struan F. A. Grant, Mingyao Li, Jonathan P. Bradfield, Cecilia E. Kim, Kiran Annaiah, Erin Santa, Joseph T. Glessner, Tracy Casalunovo, Edward C. Frackelton, F. George Otieno, Julie L. Shaner, Ryan M. Smith, Marcin Imielinski, Andrew W. Eckert, Rosetta M. Chiavacci, Robert I. Berkowitz, Hakon Hakonarson

published 12 Mar 2008

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Genome-Wide Prediction of Functional Gene-Gene Interactions Inferred from Patterns of Genetic Differentiation in Mice and Men

Zoltán Bochdanovits, David Sondervan, Sophie Perillous, Toos van Beijsterveldt, Dorret Boomsma, Peter Heutink

published 13 Feb 2008

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Genome Wide Association (GWA) Study for Early Onset Extreme Obesity Supports the Role of Fat Mass and Obesity Associated Gene (FTO) Variants

Anke Hinney, Thuy Trang Nguyen, André Scherag, Susann Friedel, Günter Brönner, Timo Dirk Müller, Harald Grallert, Thomas Illig, H.-Erich Wichmann, Winfried Rief, Helmut Schäfer, Johannes Hebebrand

published 26 Dec 2007

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