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Human genetics

Genetic insights into the risk of hip osteoarthritis on stroke: A single-variable and multivariable Mendelian randomization

Zhengze Zhang, Yanan Lian, Yuewen He, Hao Liu, Kai Meng, Yong Wang, Wuhua Ma

published 09 Jan 2025

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Patient stratification by genetic risk in Alzheimer’s disease is only effective in the presence of phenotypic heterogeneity

Jack Euesden, Muhammad Ali, Chloe Robins, Praveen Surendran, Padhraig Gormley, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI) , David Pulford, Carlos Cruchaga

published 09 Jan 2025

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Denovo variants in POGZ and YY1 genes: The novel mega players for neurodevelopmental syndromes in two unrelated consanguineous families

Behjat Ul Mudassir, Mujaddid Mudassir, Jamal B. Williams, Zehra Agha

published 08 Jan 2025

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Potential associations of selected polymorphic genetic variants with COVID-19 disease susceptibility and severity

Orsolya Mózner, Edit Szabó, Anna Kulin, György Várady, Judit Moldvay, Vivien Vass, Andrea Szentesi, Ágoston Jánosi, Péter Hegyi, Balázs Sarkadi

published 03 Jan 2025

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Block selection in multiblock partial least squares for modeling genotype-phenotype relations in Saccharomyces

Muhammad Tahir, Bu Yude, Tahir Mehmood, Saima Bashir, Zeeshan Ashraf

published 02 Jan 2025

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Shared genetic factors and the interactions with fresh fruit intake contributes to four types squamous cell carcinomas

Mengqing Mo, Can Hou, Huangbo Yuan, Renjia Zhao, Mingyang Chen, Yanfeng Jiang, Kelin Xu, Tiejun Zhang, Xingdong Chen, Chen Suo

published 31 Dec 2024

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Phenome-wide association network demonstrates close connection with individual disease trajectories from the HUNT study

Martina Hall, Marit K. Skinderhaug, Eivind Almaas

published 27 Dec 2024

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Phenotypic and molecular characterization of the largest worldwide cluster of hereditary angioedema type 1

Juan Sebastian Arias-Flórez, Sandra Ximena Ramirez, Bibiana Bayona-Gomez, Lina Castro-Castillo, Valeria Correa-Martinez, Yasmín Sanchez-Gomez, William Usaquén-Martínez, Lilian Andrea Casas-Vargas, Carlos Eduardo Olmos Olmos, Nora Contreras Bravo, Camilo Andres Velandia-Piedrahita, Adrien Morel, Rodrigo Cabrera-Perez, Natalia Santiago-Tovar, Cristian Camilo Gaviria-Sabogal, Ingrid Tatyana Bernal, Dora Janeth Fonseca-Mendoza, Carlos M. Restrepo

published 26 Dec 2024

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Molecular monitoring of short- and long-term transcriptional effects of hair growth stimulating agents

Sabrina K. Henne, Lara M. Hochfeld, Werner Bartmann, Thomas Welss, Markus M. Nöthen, Stefanie Heilmann-Heimbach

published 23 Dec 2024

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Quantitative trait loci for grain mineral element accumulation in Vietnamese rice landraces

Hien Linh Tran, Giang Thi Hoang, Nhung Thi Phuong Phung, Ham Huy Le, Alexandre Grondin, Pascal Gantet

published 23 Dec 2024

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Identifying potential drug targets for myocardial infarction through Mendelian randomization

Xiangyou Yu, Shasha Liu

published 23 Dec 2024

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Dynamics of SARS-CoV-2 lineages in children and adults in 2021 and 2022

Hiie Soeorg, Aare Abroi, Taavi Päll, Liidia Dotsenko, Erik Jaaniso, Katrin Kaarna, Andrio Lahesaare, Paul Naaber, Heiki Niglas, Ott Eric Oopkaup, Hedi Peterson, Tuuli Reisberg, Olga Sadikova, Steven Smit, Ulvi Gerst Talas, Radko Avi, Irja Lutsar, Kristi Huik

published 20 Dec 2024

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Clinical and biochemical features of atherogenic hyperlipidemias with different genetic basis: A comprehensive comparative study

Anastasia V. Blokhina, Alexandra I. Ershova, Anna V. Kiseleva, Evgeniia A. Sotnikova, Anastasia A. Zharikova, Marija Zaicenoka, Yuri V. Vyatkin, Vasily E. Ramensky, Vladimir A. Kutsenko, Olga A. Litinskaya, Maria S. Pokrovskaya, Svetlana A. Shalnova, Alexey N. Meshkov, Oxana M. Drapkina

published 20 Dec 2024

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