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Hippocampus

High frequency head impact exposure changes hippocampal sharp-wave ripple architecture

Daniel P. Chapman, Margaret S. Sten, Stefano Vicini, Mark P. Burns

published 09 Jan 2026

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The absence or the pharmacological blockade of the aryl hydrocarbon receptor promotes neuroprotection in the hippocampus after an ischemic insult

Rolando Castañeda-Arellano, Lucia García-Lara, Quetzalli D. Angeles-López, Francisca Pérez-Severiano, Guillermo Elizondo-Azuela, Sergio H. Dueñas-Jimenez, Sirenia González-Pozos, Irene G. Aguilar-García, Jose Segovia

published 26 Dec 2025

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Development of a floxed Gabbr2 gene allows for widespread conditional disruption of GABBR2 and recapitulates the phenotype of germline Gabbr2 knockout mice

Julie Rose Hens, Stacey Brown, Pawel Licznerski, Jacqueline Suarez, Elizabeth Jonas, John J. Wysolmerski

published 15 Dec 2025

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A mouse model of early sporadic tau pathology induces neurogenic plasticity in the hippocampus

Alyssa M. Ash, Sue Rim Baek, Peyton Holder, Sara Singh, Nicholas P. Vyleta, Matthew Willman, Kevin R. Nash, Jason S. Snyder

published 10 Dec 2025

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Housing environment bilaterally alters transcriptomic profile in the rat hippocampal CA1 region

Azusa Kubota, Kentaro Kojima, Shinnosuke Koketsu, Takayuki Kannon, Takehiro Sato, Kazuyoshi Hosomichi, Yoshiaki Shinohara, Atsushi Tajima

published 04 Dec 2025

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Object location memories recruit distal CA1 and catecholaminergic inputs to proximodistal CA1

Ana Paula Crestani, Yusuke Teratani-Ota, Brian Joseph Wiltgen

published 04 Dec 2025

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Shared and distinct microRNA profiles between HT22, N2A and SH-SY5Y cell lines and primary mouse hippocampal neurons

Ronan Murphy, Javier Villegas-Salmerón, Amaya Sanz-Rodriguez, Tobias Engel, Catherine Mooney, David C. Henshall, Eva M. Jimenez-Mateos

published 03 Dec 2025

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Aging and episodic memory specificity: Evidence challenging a domain-general pattern separation decline

Ariana Youm, Melanie Cohn, Katherine Duncan

published 24 Nov 2025

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Breathing mode selectively modulates brain-wide functional connectivity

Sadeq Mohammadi, Gholam-Ali Hossein-Zadeh, Mohammad Reza Raoufy

published 14 Nov 2025

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SARS-CoV-2 spike protein causes synaptic dysfunction and p-tau and α-synuclein aggregation leading cognitive impairment: The protective role of metformin

Hye-Kyung Lee, Ji Young Choi, Jung Hyun Park, Moon Han Chang, Jung Ho Park, Young Ho Koh

published 07 Nov 2025

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Semi-supervised synthesis of 7T MRI from 3T using 3D FR-U-Net with anatomical segmentation consistency assessment

Richard Acs, Hanqi Zhuang

published 06 Nov 2025

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Mature tau pathology is not improved by interfering with interleukin-1 receptor signaling in two mouse models of tauopathy

Dylan J. Finneran, Brianna M. Jackman, Taylor Desjarlais, Alayna Henry, Ahlam S. Soliman, Patricia C. Muskus, Rama Shankar, Bin Chen, Kevin R. Nash, Dave Morgan, Marcia N. Gordon

published 05 Nov 2025

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Behavioural, immunological and transcriptomic consequences of post-weaning social isolation and chronic celecoxib administration in mouse

Aodán Laighneach, Derek W. Morris, Saahithh Redddi Patlola, Marcelo Improta, Lieve Desbonnet, Gary Donohoe, John P. Kelly, Declan P. McKernan

published 22 Oct 2025

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