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High throughput screening

Isolation and Biochemical Characterization of a Glucose Dehydrogenase from a Hay Infusion Metagenome

Alexander Basner, Garabed Antranikian

published 14 Jan 2014

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Inhibition of DNA Glycosylases via Small Molecule Purine Analogs

Aaron C. Jacobs, Marcus J. Calkins, Ajit Jadhav, Dorjbal Dorjsuren, David Maloney, Anton Simeonov, Pawel Jaruga, Miral Dizdaroglu, Amanda K. McCullough, R. Stephen Lloyd

published 09 Dec 2013

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Molecular Engineering of Fungal GH5 and GH26 Beta-(1,4)-Mannanases toward Improvement of Enzyme Activity

Marie Couturier, Julia Féliu, Sophie Bozonnet, Alain Roussel, Jean-Guy Berrin

published 22 Nov 2013

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Development and Implementation of a High-Throughput Compound Screening Assay for Targeting Disrupted ER Calcium Homeostasis in Alzheimer's Disease

Kamran Honarnejad, Alexander Daschner, Armin Giese, Andrea Zall, Boris Schmidt, Aleksandra Szybinska, Jacek Kuznicki, Jochen Herms

published 15 Nov 2013

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Improved Activity of a Thermophilic Cellulase, Cel5A, from Thermotoga maritima on Ionic Liquid Pretreated Switchgrass

Zhiwei Chen, Jose H. Pereira, Hanbin Liu, Huu M. Tran, Nathan S. Y. Hsu, Dean Dibble, Seema Singh, Paul D. Adams, Rajat Sapra, Masood Z. Hadi, Blake A. Simmons, Kenneth L. Sale

published 14 Nov 2013

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A High-Throughput Screen against Pantothenate Synthetase (PanC) Identifies 3-Biphenyl-4-Cyanopyrrole-2-Carboxylic Acids as a New Class of Inhibitor with Activity against Mycobacterium tuberculosis

Anuradha Kumar, Allen Casey, Joshua Odingo, Edward A. Kesicki, Garth Abrahams, Michal Vieth, Thierry Masquelin, Valerie Mizrahi, Philip A. Hipskind, David R. Sherman, Tanya Parish

published 07 Nov 2013

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Rapid Mutation of Spirulina platensis by a New Mutagenesis System of Atmospheric and Room Temperature Plasmas (ARTP) and Generation of a Mutant Library with Diverse Phenotypes

Mingyue Fang, Lihua Jin, Chong Zhang, Yinyee Tan, Peixia Jiang, Nan Ge, Heping Li, Xinhui Xing

published 11 Oct 2013

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A Microliter-Scale High-throughput Screening System with Quantum-Dot Nanoprobes for Amyloid-β Aggregation Inhibitors

Yukako Ishigaki, Hiroyuki Tanaka, Hiroaki Akama, Toshiki Ogara, Koji Uwai, Kiyotaka Tokuraku

published 26 Aug 2013

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Identification of a Novel Sulfonamide Non-Nucleoside Reverse Transcriptase Inhibitor by a Phenotypic HIV-1 Full Replication Assay

Tae-Hee Kim, Yoonae Ko, Thierry Christophe, Jonathan Cechetto, Junwon Kim, Kyoung-Ae Kim, Annette S. Boese, Jean-Michel Garcia, Denis Fenistein, Moon Kyeong Ju, Junghwan Kim, Sung-Jun Han, Ho Jeong Kwon, Vincent Brondani, Peter Sommer

published 18 Jul 2013

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A Rapid and Sensitive Method for Measuring N-Acetylglucosaminidase Activity in Cultured Cells

Victor Mauri, Parisa Lotfi, Laura Segatori, Marco Sardiello

published 28 Jun 2013

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High-Throughput Screening for GPR119 Modulators Identifies a Novel Compound with Anti-Diabetic Efficacy in db/db Mice

Meng Zhang, Yang Feng, Jia Wang, Jianwei Zhao, Ting Li, Min He, Dehua Yang, Olivier Nosjean, Jean Boutin, Pierre Renard, Ming-Wei Wang

published 21 May 2013

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Identification of Adiponectin Receptor Agonist Utilizing a Fluorescence Polarization Based High Throughput Assay

Yiyi Sun, Zhihe Zang, Ling Zhong, Min Wu, Qing Su, Xiurong Gao, Wang Zan, Dong Lin, Yan Zhao, Zhonglin Zhang

published 14 May 2013

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Screening Compounds with a Novel High-Throughput ABCB1-Mediated Efflux Assay Identifies Drugs with Known Therapeutic Targets at Risk for Multidrug Resistance Interference

Megan R. Ansbro, Suneet Shukla, Suresh V. Ambudkar, Stuart H. Yuspa, Luowei Li

published 10 Apr 2013

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