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High throughput screening

A Comparison of Protein Kinases Inhibitor Screening Methods Using Both Enzymatic Activity and Binding Affinity Determination

Amalie Frederikke Rudolf, Tine Skovgaard, Stefan Knapp, Lars Juhl Jensen, Jens Berthelsen

published 10 Jun 2014

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iRFP Is a Real Time Marker for Transformation Based Assays in High Content Screening

Viola Paulus-Hock, Eric C. Cheung, Patricia Roxburgh, Karen H. Vousden, Andreas K. Hock

published 02 Jun 2014

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Toward Discovering New Anti-Cancer Agents Targeting Topoisomerase IIα: A Facile Screening Strategy Adaptable to High Throughput Platform

Yu-Shih Lin, Wan-Chen Huang, Mei-Shya Chen, Tao-shih Hsieh

published 08 May 2014

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Identification of Isoxsuprine Hydrochloride as a Neuroprotectant in Ischemic Stroke through Cell-Based High-Throughput Screening

Jeff W. Hill, Jeffrey F. Thompson, Mark B. Carter, Bruce S. Edwards, Larry A. Sklar, Gary A. Rosenberg

published 07 May 2014

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Filtration Improves the Performance of a High-Throughput Screen for Anti-Mycobacterial Compounds

Nancy Cheng, Melissa A. Porter, Lloyd W. Frick, Yvonne Nguyen, Jennifer D. Hayden, Ellen F. Young, Miriam S. Braunstein, Emily A. Hull-Ryde, William P. Janzen

published 02 May 2014

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Identification of Resveratrol Oligomers as Inhibitors of Cystic Fibrosis Transmembrane Conductance Regulator by High-Throughput Screening of Natural Products from Chinese Medicinal Plants

Yaofang Zhang, Bo Yu, Yujie Sui, Xin Gao, Hong Yang, Tonghui Ma

published 08 Apr 2014

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A High Throughput Screening Assay System for the Identification of Small Molecule Inhibitors of gsp

Nisan Bhattacharyya, Xin Hu, Catherine Z. Chen, Lesley A. Mathews Griner, Wei Zheng, James Inglese, Christopher P. Austin, Juan J. Marugan, Noel Southall, Susanne Neumann, John K. Northup, Marc Ferrer, Michael T. Collins

published 25 Mar 2014

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High-Throughput Screening Reveals Alsterpaullone, 2-Cyanoethyl as a Potent p27Kip1 Transcriptional Inhibitor

Brandon J. Walters, Wenwei Lin, Shiyong Diao, Mark Brimble, Luigi I. Iconaru, Jennifer Dearman, Asli Goktug, Taosheng Chen, Jian Zuo

published 19 Mar 2014

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High-Throughput Screening Identifies Idarubicin as a Preferential Inhibitor of Smooth Muscle versus Endothelial Cell Proliferation

Shakti A. Goel, Lian-Wang Guo, Bowen Wang, Song Guo, Drew Roenneburg, Gene E. Ananiev, F. Michael Hoffmann, K. Craig Kent

published 24 Feb 2014

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Discovery of Selective Inhibitors of the Clostridium difficile Dehydroquinate Dehydratase

Kiira Ratia, Samuel H. Light, Aleksandar Antanasijevic, Wayne F. Anderson, Michael Caffrey, Arnon Lavie

published 21 Feb 2014

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Polydiacetylene-Based High-Throughput Screen for Surfactin Producing Strains of Bacillus subtilis

Lingyan Zhu, Qing Xu, Ling Jiang, He Huang, Shuang Li

published 03 Feb 2014

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Isolation and Biochemical Characterization of a Glucose Dehydrogenase from a Hay Infusion Metagenome

Alexander Basner, Garabed Antranikian

published 14 Jan 2014

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Inhibition of DNA Glycosylases via Small Molecule Purine Analogs

Aaron C. Jacobs, Marcus J. Calkins, Ajit Jadhav, Dorjbal Dorjsuren, David Maloney, Anton Simeonov, Pawel Jaruga, Miral Dizdaroglu, Amanda K. McCullough, R. Stephen Lloyd

published 09 Dec 2013

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