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High throughput screening

Global Analysis Reveals Families of Chemical Motifs Enriched for hERG Inhibitors

Fang Du, Joseph J. Babcock, [ ... ], Min Li

Identification of Adiponectin Receptor Agonist Utilizing a Fluorescence Polarization Based High Throughput Assay

Yiyi Sun, Zhihe Zang, [ ... ], Zhonglin Zhang

A High-Throughput Assay for Small Molecule Destabilizers of the KRAS Oncoprotein

Joseph Carver, Thomas S. Dexheimer, [ ... ], Ji Luo

Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators

Kathryn M. Hart, Katelyn E. Moeder, [ ... ], Gregory R. Bowman

Pharmacological Targeting of Native CatSper Channels Reveals a Required Role in Maintenance of Sperm Hyperactivation

Anne E. Carlson, Lindsey A. Burnett, [ ... ], Donner F. Babcock

Isolation and Biochemical Characterization of a Glucose Dehydrogenase from a Hay Infusion Metagenome

Alexander Basner, Garabed Antranikian

Automated Analysis of NF-κB Nuclear Translocation Kinetics in High-Throughput Screening

Zi Di, Bram Herpers, [ ... ], John H. N. Meerman

Inhibition of DNA Glycosylases via Small Molecule Purine Analogs

Aaron C. Jacobs, Marcus J. Calkins, [ ... ], R. Stephen Lloyd

New Classes of Alanine Racemase Inhibitors Identified by High-Throughput Screening Show Antimicrobial Activity against Mycobacterium tuberculosis

Karen G. Anthony, Ulrich Strych, [ ... ], Raymond A. Koski

Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε

Jessica E. Hutti, Melissa A. Porter, [ ... ], William P. Janzen

GUItars: A GUI Tool for Analysis of High-Throughput RNA Interference Screening Data

Asli N. Goktug, Su Sien Ong, Taosheng Chen

A Multi-Parameter, High-Content, High-Throughput Screening Platform to Identify Natural Compounds that Modulate Insulin and Pdx1 Expression

Jessica A. Hill, Marta Szabat, [ ... ], James D. Johnson

High-Throughput 1,536-Well Fluorescence Polarization Assays for α₁-Acid Glycoprotein and Human Serum Albumin Binding

Adam Yasgar, Silviya D. Furdas, [ ... ], Anton Simeonov

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