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High throughput screening

Functional Metagenomics: A High Throughput Screening Method to Decipher Microbiota-Driven NF-κB Modulation in the Human Gut

Omar Lakhdari, Antonietta Cultrone, Julien Tap, Karine Gloux, Françoise Bernard, S. Dusko Ehrlich, Fabrice Lefèvre, Joël Doré, Hervé M. Blottière

published 30 Sep 2010

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A Multi-Parameter, High-Content, High-Throughput Screening Platform to Identify Natural Compounds that Modulate Insulin and Pdx1 Expression

Jessica A. Hill, Marta Szabat, Corinne A. Hoesli, Blair K. Gage, Yu Hsuan C. Yang, David E. Williams, Michael J. Riedel, Dan S. Luciani, Tatyana B. Kalynyak, Kevin Tsai, Ziliang Ao, Raymond J. Andersen, Garth L. Warnock, James M. Piret, Timothy J. Kieffer, James D. Johnson

published 23 Sep 2010

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Genome-Wide Scoring of Positive and Negative Epistasis through Decomposition of Quantitative Genetic Interaction Fitness Matrices

Ville-Pekka Eronen, Rolf O. Lindén, Anna Lindroos, Mirella Kanerva, Tero Aittokallio

published 15 Jul 2010

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Quantitative Modeling of the High-Throughput Production and In Vivo Kinetics of (Drug-Encapsulating) Liposomes

Albert Wong

published 23 Apr 2010

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Analysis of Compound Synergy in High-Throughput Cellular Screens by Population-Based Lifetime Modeling

Martin Peifer, Jonathan Weiss, Martin L. Sos, Mirjam Koker, Stefanie Heynck, Christian Netzer, Stefanie Fischer, Haridas Rode, Daniel Rauh, Jörg Rahnenführer, Roman K. Thomas

published 27 Jan 2010

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Discovery of Novel Proteasome Inhibitors Using a High-Content Cell-Based Screening System

Irena Lavelin, Avital Beer, Zvi Kam, Varda Rotter, Moshe Oren, Ami Navon, Benjamin Geiger

published 30 Dec 2009

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A High-Throughput Approach for Identification of Novel General Anesthetics

Wendy A. Lea, Jin Xi, Ajit Jadhav, Louis Lu, Christopher P. Austin, Anton Simeonov, Roderic G. Eckenhoff

published 24 Sep 2009

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Pharmacological Targeting of Native CatSper Channels Reveals a Required Role in Maintenance of Sperm Hyperactivation

Anne E. Carlson, Lindsey A. Burnett, Donato del Camino, Timothy A. Quill, Bertil Hille, Jayhong A. Chong, Magdalene M. Moran, Donner F. Babcock

published 31 Aug 2009

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Small-Molecule Activators of Insulin-Degrading Enzyme Discovered through High-Throughput Compound Screening

Christelle Cabrol, Malwina A. Huzarska, Christopher Dinolfo, Maria C. Rodriguez, Lael Reinstatler, Jake Ni, Li-An Yeh, Gregory D. Cuny, Ross L. Stein, Dennis J. Selkoe, Malcolm A. Leissring

published 22 Apr 2009

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Kinetic Analysis of Yersinia pestis DNA Adenine Methyltransferase Activity Using a Hemimethylated Molecular Break Light Oligonucleotide

Robert J. Wood, Michael D. Maynard-Smith, Victoria L. Robinson, Petra C.F. Oyston, Rick W. Titball, Peter L. Roach

published 29 Aug 2007

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