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High throughput screening

A high-throughput inhibitor screen for the erythrocyte plasma membrane Ca⁺⁺ ATPase

Jonathan Chu, Shreyas Annaswamy, Sanjay A. Desai

published 25 Jun 2026

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RETRACTED: Advanced machine learning-guided optimization platform for high-yield soluble expression of Pseudomonas aeruginosa exotoxin A in engineered Escherichia coli strains

Shah Faisal Mohammad, Fawad Ali, Mamirkulova Shynara

published 10 Apr 2026

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Protective effect of cannabinoid type II receptor ligand on bleomycin-induced pulmonary fibrosis in mice

Cheng Cao, Run-Lin Wang, Chen-xin Guo, Xiao-wei Xu, Jia-hui Wei, Wen-zhuo Cheng, Yi-zhe Yu, Jia-jie Shi, Zhi-wei Feng, Yan Chen

published 27 Feb 2026

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RamanBot: Versatile high throughput Raman system

Khaled Atia, Robert Hunter, Meshach Asare-Werehene, Benjamin K. Tsang, Hanan Anis

published 13 Jan 2026

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A water solubility prediction algorithm based on the StackBoost model

Bin Pan, Xiaoyu Hou, Mingxin Zhang, Jingxian Yu, Conghui Zhang, Yunhui Zhang, Xiaolong Su, Shuangcai Li

published 29 Aug 2025

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Identification of glutathione transferase (GST P1) inhibitors via a high-throughput screening assay and implications as alternative treatment options for breast cancers

Sarah A. P. Pereira, Jonathan Vesin, Marc Chambon, Gerardo Turcatti, M. Lúcia M. F. S. Saraiva, Paul J. Dyson

published 24 Jul 2025

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Pharmacophore modeling and QSAR analysis of anti-HBV flavonols

Basireh Baei, Parnia Askari, Fatemeh Sana Askari, Seyed Jalal Kiani, Alireza Mohebbi

published 13 Jan 2025

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Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease

Jian-Ping Yang, Rachel Toughiri, Anshu P. Gounder, Dan Scheibe, Matt Petrus, Sarah J. Fink, Sebastien Vallee, Jon Kenniston, Nikolaos Papaioannou, Steve Langston, Narender R. Gavva, Shane R. Horman

published 06 Nov 2024

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A novel small molecule screening assay using normal human chondrocytes toward osteoarthritis drug discovery

Philip R. Coryell, Paul B. Hardy, Susan Chubinskaya, Kenneth H. Pearce, Richard F. Loeser

published 01 Nov 2024

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A homogeneous time-resolved fluorescence screen to identify SIRT2 deacetylase and defatty-acylase inhibitors

Jie Yang, Joel Cassel, Brian C. Boyle, Daniel Oppong, Young-Hoon Ahn, Brian P. Weiser

published 24 Jun 2024

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HTSplotter: An end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening

Carolina Nunes, Jasper Anckaert, Fanny De Vloed, Jolien De Wyn, Kaat Durinck, Jo Vandesompele, Frank Speleman, Vanessa Vermeirssen

published 05 Jan 2024

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High-throughput phenotypic screen identifies a new family of potent anti-amoebic compounds

Conall Sauvey, Ittipat Meewan, Gretchen Ehrenkaufer, Jonathan Blevitt, Paul Jackson, Ruben Abagyan

published 09 May 2023

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A high-throughput newborn screening approach for SCID, SMA, and SCD combining multiplex qPCR and tandem mass spectrometry

Rafael Tesorero, Joachim Janda, Friederike Hörster, Patrik Feyh, Ulrike Mütze, Jana Hauke, Kathrin Schwarz, Joachim B. Kunz, Georg F. Hoffmann, Jürgen G. Okun

published 10 Mar 2023

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