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HeLa cells

The N-terminal activation function AF-1 domain of ERα interacts directly with the C-terminal AF-2-holding ligand-binding domain to recruit the coactivator proteins

Xiaohui Liu, Yutaka Matsuyama, Makiko Sugiyama, Keitaro Suyama, Takeru Nose, Miki Shimohigashi, Yasuyuki Shimohigashi

published 21 Oct 2024

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Isoginkgetin and Madrasin are poor splicing inhibitors

Michael Tellier, Gilbert Ansa, Shona Murphy

published 21 Oct 2024

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Visualizing VDAC1 in live cells using a tetracysteine tag

Johannes Pilic, Furkan E. Oflaz, Benjamin Gottschalk, Yusuf C. Erdogan, Wolfgang F. Graier, Roland Malli

published 18 Oct 2024

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Synergistic celecoxib and dimethyl-celecoxib combinations block cervix cancer growth through multiple mechanisms

Diana Xochiquetzal Robledo-Cadena, Silvia Cecilia Pacheco-Velázquez, Jorge Luis Vargas-Navarro, Joaquín Alberto Padilla-Flores, Rebeca López-Marure, Israel Pérez-Torres, Tuuli Kaambre, Rafael Moreno-Sánchez, Sara Rodríguez-Enríquez

published 26 Sep 2024

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An expeditious and facile method of amyloid beta (1–42) purification

Md. Aminul Haque, Il Seon Park

published 11 Jul 2024

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Glyoxalase 1: Emerging biomarker and therapeutic target in cervical cancer progression

Ji-Young Kim, Ji-Hye Jung, Soryung Jung, Sanghyuk Lee, Hyang Ah Lee, Yung-Taek Ouh, Seok-Ho Hong

published 13 Jun 2024

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Acute toxicity appraisal of Saussurea heteromalla extract and development of its chemotherapeutic herbal dosage form

Azra Batool, Muhammad Muddassir, Basmah H. Alshammari, Tariq G. Alsahli, Gideon F. B. Solre, Yanting Liu, Muhammad Tariq Khan, Nadia Shamshad Malik, Hina Ahsan, Muhammad Tahir Khan, Muhammad Nasir Hayat Malik, Ghulam Abbas Miana

published 24 May 2024

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Substrate preference of protein kinase B isoforms can vary depending on the cell line

Miguel S. Palma, Samantha R. Perez, Aida Husain, Deepali Bhandari

published 19 Mar 2024

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Pomegranate extract-loaded sphingosomes for the treatment of cancer: Phytochemical investigations, formulation, and antitumor activity evaluation

Huda Jamal AlMadalli, Bazigha K. Abdul Rasool, Naglaa Gamil Shehab, Francesca Della Sala, Assunta Borzacchiello

published 12 Feb 2024

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TXNIP-mediated crosstalk between oxidative stress and glucose metabolism

Stephanie Kim, Jianning Ge, Dokyun Kim, Jae Jin Lee, Youn Jung Choi, Weiqiang Chen, James W. Bowman, Suan-Sin Foo, Lin-Chun Chang, Qiming Liang, Daiki Hara, Inpyo Choi, Myung Hee Kim, Hyungjin Eoh, Jae U. Jung

published 08 Feb 2024

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Identification of MYC intron 2 regions that modulate expression

Van S. Tompkins, Zheng Xue, Jake M. Peterson, Warren B. Rouse, Collin A. O’Leary, Walter N. Moss

published 18 Jan 2024

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Cell cycle regulation of the psoriasis associated gene CCHCR1 by transcription factor E2F1

Yick Hin Ling, Yingying Chen, Kwok Nam Leung, King Ming Chan, W. K. Liu

published 21 Dec 2023

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USP7 attenuates endoplasmic reticulum stress-induced apoptotic cell death through deubiquitination and stabilization of FBXO7

Su Hyoun Lee, Kwang Chul Chung

published 24 Oct 2023

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