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Heart

Cardiac digital twins at scale from MRI: Open tools and representative models from ~ 55000 UK Biobank participants

Devran Ugurlu, Shuang Qian, Elliot Fairweather, Charlene Mauger, Bram Ruijsink, Laura Dal Toso, Yu Deng, Marina Strocchi, Reza Razavi, Alistair Young, Pablo Lamata, Steven Niederer, Martin Bishop

published 15 Jul 2025

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Desmin disorganisation: A key feature in feline hypertrophic cardiomyopathy

Wan-Ching Cheng, Charlotte Lawson, Lois Wilkie, Melanie Dobromylsky, Virginia Luis Fuentes, Mark R. Holt, Elisabeth Ehler, David J. Connolly

published 14 Jul 2025

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Metabolomics analysis and mRNA/miRNA profiling reveal potential cardiac regulatory mechanisms in Yili racehorses under different training regimens

Tongliang Wang, Jun Meng, Xuan Peng, Jinlong Huang, Yunjiang Huang, Xinxin Yuan, Xueyan Li, Xixi Yang, Xiaokang Chang, Yaqi Zeng, Xinkui Yao

published 14 Jul 2025

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Weighted Hypoxemia Index: An adaptable method for quantifying hypoxemia severity

Diane C. Lim, Cheng-Bang Chen, Ankita Paul, Yujie Wang, Jinyoung Kim, Soonhyun Yook, Emily Y. Kim, Edison Q. Kim, Anup Das, Medhi Wangpaichitr, Virend K. Somers, Chi Hang Lee, Phyllis C. Zee, Toshihiro Imamura, Hosung Kim

published 10 Jul 2025

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Morphological characterization of indigenous goats in selected districts of West Shewa Zone, Oromia regional State, Ethiopia

Kassahun Bekana Kitila, Abera Teshome Aleli, Solomon Shiferaw Tufa

published 09 Jul 2025

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Interpretable machine learning for predicting isolated basal septal hypertrophy

Lei Gao, Boyan Tian, Qiqi Jia, Xingyu He, Guannan Zhao, Yueheng Wang

published 30 Jun 2025

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Left ventricular segmentation method based on optimized UNet and improved CBAM: ESV and EDV tracking study

Kerang Cao, Miao Zhao, Minghui Geng, Shuai Zheng, Hoekyung Jung

published 25 Jun 2025

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The impact of experimental designs & system sloppiness on the personalisation process: A cardiovascular perspective

Harry Saxton, Daniel J. Taylor, Grace Faulkner, Ian Halliday, Tom Newman, Torsten Schenkel, Paul D. Morris, Richard H. Clayton, Xu Xu

published 24 Jun 2025

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Sox9 in the epicardium: Implications for cell invasion, differentiation, and coronary vascular development

Andrew B. Harvey, Allison M. Trouten, Renélyn A. Wolters, Jenna R. Drummond, Raymond N. Deepe, Hannah G. Tarolli, Inara Devji, Silvia G. Vaena, Martin J. Romeo, Robin Muise-Helmericks, Paula S. Ramos, Russell A. Norris, Ge Tao, Andy Wessels

published 23 Jun 2025

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TENS alone or combined with low-level laser therapy photobiomodulation for pain, functional capacity, and cardiorespiratory physiological variables after cesarean section: protocol for a randomized clinical trial

Alane Macatrão Pires de Holanda Araújo Sena, Ivan Daniel Bezerra Nogueira, Kássio Rafael Rocha de Sena, Patrícia Angélica de Miranda Silva Nogueira

published 20 Jun 2025

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Emulating the EPIC trial using VetCompass primary-care data: causal effects of pimobendan in UK dogs with grade IV/VI heart murmurs

Camilla Pegram, Karla Diaz-Ordaz, Dave C. Brodbelt, Yu-Mei Chang, Adrian Boswood, Jenny Wilshaw, Carmen A. T. Reep, Sarah Balling, Jaya Sahota, David B. Church, Dan G. O’Neill

published 18 Jun 2025

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Epac1 increases myosin regulatory light-chain phosphorylation, energetic cost of contraction, and susceptibility to heart failure

Yoshiki Ohnuki, Kenji Suita, Misao Ishikawa, Yasumasa Mototani, Megumi Nariyama, Aiko Ito, Ichiro Matsuo, Yoshio Hayakawa, Akinaka Morii, Takao Mitsubayashi, Yasutake Saeki, Yoshihiro Ishikawa, Satoshi Okumura

published 17 Jun 2025

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Enhancing ECG disease detection accuracy through deep learning models and P-QRS-T waveform features

Rida Nayyab, Asim Waris, Iqra Zaheer, Muhammad Jawad Khan, Fawwaz Hazzazi, Muhammad Adeel Ijaz, Hassan Ashraf, Syed Omer Gilani

published 10 Jun 2025

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