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Glutamine

Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition

Michael Lampa, Heike Arlt, Timothy He, Beatriz Ospina, Jason Reeves, Bailin Zhang, Joshua Murtie, Gejing Deng, Claude Barberis, Dietmar Hoffmann, Hong Cheng, Jack Pollard, Christopher Winter, Victoria Richon, Carlos Garcia-Escheverria, Francisco Adrian, Dmitri Wiederschain, Lakshmi Srinivasan

published 26 Sep 2017

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Increased plasma proline concentrations are associated with sarcopenia in the elderly

Kenji Toyoshima, Marie Nakamura, Yusuke Adachi, Akira Imaizumi, Tomomi Hakamada, Yasuko Abe, Eiji Kaneko, Soiciro Takahashi, Kentaro Shimokado

published 21 Sep 2017

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Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo ¹H MR spectroscopy

Hester Rijkje Berger, Axel K. G. Nyman, Tora Sund Morken, Riyas Vettukattil, Ann-Mari Brubakk, Marius Widerøe

published 21 Sep 2017

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Analysis of simple sequence repeat (SSR) structure and sequence within Epichloë endophyte genomes reveals impacts on gene structure and insights into ancestral hybridization events

William Clayton, Carla Jane Eaton, Pierre-Yves Dupont, Tim Gillanders, Nick Cameron, Sanjay Saikia, Barry Scott

published 08 Sep 2017

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Nitrogen uptake and assimilation in proliferating embryogenic cultures of Norway spruce—Investigating the specific role of glutamine

Johanna Carlsson, Henrik Svennerstam, Thomas Moritz, Ulrika Egertsdotter, Ulrika Ganeteg

published 24 Aug 2017

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Enhancement of the production of _L-glutaminase, an anticancer enzyme, from Aeromonas veronii by adaptive and induced mutation techniques

S. Aravinth Vijay Jesuraj, Md. Moklesur Rahman Sarker, Long Chiau Ming, S. Marylin Jeya Praya, M. Ravikumar, Wong Tin Wui

published 16 Aug 2017

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Regulation of hepatic stellate cell proliferation and activation by glutamine metabolism

Jiang Li, Mohammed Ghazwani, Ke Liu, Yixian Huang, Na Chang, Jie Fan, Fengtian He, Liying Li, Shizhong Bu, Wen Xie, Xiaochao Ma, Song Li

published 10 Aug 2017

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Molecular dynamics analysis of the aggregation propensity of polyglutamine segments

Jingran Wen, Daniel R. Scoles, Julio C. Facelli

published 25 May 2017

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MUC1 facilitates metabolomic reprogramming in triple-negative breast cancer

Gennifer Goode, Venugopal Gunda, Nina V. Chaika, Vinee Purohit, Fang Yu, Pankaj K. Singh

published 02 May 2017

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Pyridoxal phosphate synthases PdxS/PdxT are required for Actinobacillus pleuropneumoniae viability, stress tolerance and virulence

Fang Xie, Gang Li, Yalei Wang, Yanhe Zhang, Long Zhou, Chengcheng Wang, Shuanghong Liu, Siguo Liu, Chunlai Wang

published 27 Apr 2017

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Comparative transcriptome and proteome analysis reveals a global impact of the nitrogen regulators AreA and AreB on secondary metabolism in Fusarium fujikuroi

Andreas Pfannmüller, Johannes Leufken, Lena Studt, Caroline B. Michielse, Christian M. K. Sieber, Ulrich Güldener, Susan Hawat, Michael Hippler, Christian Fufezan, Bettina Tudzynski

published 25 Apr 2017

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Faster flux of neurotransmitter glutamate during seizure — Evidence from ¹³C-enrichment of extracellular glutamate in kainate rat model

Keiko Kanamori

published 12 Apr 2017

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A neuronal MCT2 knockdown in the rat somatosensory cortex reduces both the NMR lactate signal and the BOLD response during whisker stimulation

Leslie Mazuel, Jordy Blanc, Cendrine Repond, Véronique Bouchaud, Gérard Raffard, Nicole Déglon, Gilles Bonvento, Luc Pellerin, Anne-Karine Bouzier-Sore

published 07 Apr 2017

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