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Glucose tolerance

Preclinical evaluation of a protracted GLP-1/glucagon receptor co-agonist: Translational difficulties and pitfalls

Lotte Simonsen, Jesper Lau, Thomas Kruse, Tingqing Guo, Jim McGuire, Jacob Fuglsbjerg Jeppesen, Kristoffer Niss, Per Sauerberg, Kirsten Raun, Charlotta Dornonville de la Cour

published 04 Mar 2022

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Insulin secretory and antidiabetic actions of Heritiera fomes bark together with isolation of active phytomolecules

Prawej Ansari, Peter R. Flatt, Patrick Harriott, Yasser H. A. Abdel-Wahab

published 03 Mar 2022

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SUR1-E1506K mutation impairs glucose tolerance and promotes vulnerable atherosclerotic plaque phenotype in hypercholesterolemic mice

Erika Gurzeler, Anna-Kaisa Ruotsalainen, Anssi Laine, Teemu Valkama, Sanna Kettunen, Markku Laakso, Seppo Ylä-Herttuala

published 12 Nov 2021

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Litter expansion alters metabolic homeostasis in a sex specific manner

Kavitha Kurup, Shivani N. Mann, Jordan Jackson, Stephanie Matyi, Michelle Ranjo-Bishop, Willard M. Freeman, Michael B. Stout, Arlan Richardson, Archana Unnikrishnan

published 29 Sep 2021

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Hypoglycemic active principles from the leaves of Bauhinia holophylla: Comprehensive phytochemical characterization and in vivo activity profile

Luiz Leonardo Saldanha, Aislan Quintiliano Delgado, Laurence Marcourt, Nathalia Aparecida de Paula Camaforte, Priscilla Maria Ponce Vareda, Samad Nejad Ebrahimi, Wagner Vilegas, Anne Lígia Dokkedal, Emerson Ferreira Queiroz, Jean-Luc Wolfender, José Roberto Bosqueiro

published 24 Sep 2021

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Structural changes in endocrine pancreas of male Wistar rats due to chronic cola drink consumption. Role of PDX-1

Gabriel Cao, Julián González, Juan P. Ortiz Fragola, Angélica Muller, Mariano Tumarkin, Marisa Moriondo, Francisco Azzato, Manuel Vazquez Blanco, José Milei

published 11 Jun 2021

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Use of hemoglobin A1c to identify dysglycemia in cystic fibrosis

Amy Darukhanavala, Filia Van Dessel, Jannifer Ho, Megan Hansen, Ted Kremer, David Alfego

published 21 Apr 2021

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Antidiabetic effects of betulinic acid mediated by the activation of the AMP-activated protein kinase pathway

Tae-Jun Song, Choon-Ho Park, Kyu-Ree In, Jong-Bae Kim, Joo Hee Kim, Miran Kim, Hye Jin Chang

published 05 Apr 2021

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Chronic peptide-based GIP receptor inhibition exhibits modest glucose metabolic changes in mice when administered either alone or combined with GLP-1 agonism

Jason A. West, Anastasia Tsakmaki, Soumitra S. Ghosh, David G. Parkes, Rikke V. Grønlund, Philip J. Pedersen, David Maggs, Harith Rajagopalan, Gavin A. Bewick

published 31 Mar 2021

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The fat mass and obesity-associated (FTO) gene allele rs9939609 and glucose tolerance, hepatic and total insulin sensitivity, in adults with obesity

Ann Kristin Hjelle de Soysa, Mette Langaas, Anida Jakic, Fariba Shojaee-Moradie, A. Margot Umpleby, Valdemar Grill, Ingrid Løvold Mostad

published 08 Mar 2021

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Cost-effectiveness of the Da Qing diabetes prevention program: A modelling study

Wanxia Hu, Wenhua Xu, Lei Si, Cuilian Wang, Qicheng Jiang, Lidan Wang, Henry Cutler

published 31 Dec 2020

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Development of a fasting blood glucose-based strategy to diagnose women with gestational diabetes mellitus at increased risk of adverse outcomes in a COVID-19 environment

Michael d’Emden, Donald McLeod, Jacobus Ungerer, Charles Appleton, David Kanowski

published 03 Dec 2020

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High levels of maternal total tri-iodothyronine, and low levels of fetal free L-thyroxine and total tri-iodothyronine, are associated with altered deiodinase expression and activity in placenta with gestational diabetes mellitus

Sebastián Gutiérrez-Vega, Axel Armella, Daniela Mennickent, Marco Loyola, Ambart Covarrubias, Bernel Ortega-Contreras, Carlos Escudero, Marcelo Gonzalez, Martín Alcalá, María del Pilar Ramos, Marta Viana, Erica Castro, Andrea Leiva, Enrique Guzmán-Gutiérrez

published 24 Nov 2020

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