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Geriatric ophthalmology

The ERCC6 Gene and Age-Related Macular Degeneration

Dominique C. Baas, Dominiek D. Despriet, Theo G. M. F. Gorgels, Julie Bergeron-Sawitzke, André G. Uitterlinden, Albert Hofman, Cornelia M. van Duijn, Joanna E. Merriam, R. Theodore Smith, Gaetano R. Barile, Jacoline B. ten Brink, Johannes R. Vingerling, Caroline C. W. Klaver, Rando Allikmets, Michael Dean, Arthur A. B. Bergen

published 01 Nov 2010

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αB Crystallin Is Apically Secreted within Exosomes by Polarized Human Retinal Pigment Epithelium and Provides Neuroprotection to Adjacent Cells

Parameswaran G. Sreekumar, Ram Kannan, Mizuki Kitamura, Christine Spee, Ernesto Barron, Stephen J. Ryan, David R. Hinton

published 08 Oct 2010

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Microglia in the Mouse Retina Alter the Structure and Function of Retinal Pigmented Epithelial Cells: A Potential Cellular Interaction Relevant to AMD

Wenxin Ma, Lian Zhao, Aurora M. Fontainhas, Robert N. Fariss, Wai T. Wong

published 20 Nov 2009

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CFH, C3 and ARMS2 Are Significant Risk Loci for Susceptibility but Not for Disease Progression of Geographic Atrophy Due to AMD

Hendrik P. N. Scholl, Monika Fleckenstein, Lars G. Fritsche, Steffen Schmitz-Valckenberg, Arno Göbel, Christine Adrion, Christine Herold, Claudia N. Keilhauer, Friederike Mackensen, Andreas Mößner, Daniel Pauleikhoff, Andreas W. A. Weinberger, Ulrich Mansmann, Frank G. Holz, Tim Becker, Bernhard H. F. Weber

published 12 Oct 2009

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rs5888 Variant of SCARB1 Gene Is a Possible Susceptibility Factor for Age-Related Macular Degeneration

Jennyfer Zerbib, Johanna M. Seddon, Florence Richard, Robyn Reynolds, Nicolas Leveziel, Pascale Benlian, Patrick Borel, Josué Feingold, Arnold Munnich, Gisèle Soubrane, Josseline Kaplan, Jean-Michel Rozet, Eric H. Souied

published 05 Oct 2009

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Mitochondrial DNA Variants of Respiratory Complex I that Uniquely Characterize Haplogroup T2 Are Associated with Increased Risk of Age-Related Macular Degeneration

John Paul SanGiovanni, Dan E. Arking, Sudha K. Iyengar, Michael Elashoff, Traci E. Clemons, George F. Reed, Alice K. Henning, Theru A. Sivakumaran, Xuming Xu, Andrew DeWan, Elvira Agrón, Elena Rochtchina, Carolyn M. Sue, Jie Jin Wang, Paul Mitchell, Josephine Hoh, Peter J. Francis, Michael L. Klein, Emily Y. Chew, Aravinda Chakravarti

published 12 May 2009

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Changes in Retinal Pigment Epithelium Related to Cigarette Smoke: Possible Relevance to Smoking as a Risk Factor for Age-Related Macular Degeneration

Ai Ling Wang, Thomas J. Lukas, Ming Yuan, Nga Du, James T. Handa, Arthur H. Neufeld

published 24 Apr 2009

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Autophagy and Exosomes in the Aged Retinal Pigment Epithelium: Possible Relevance to Drusen Formation and Age-Related Macular Degeneration

Ai Ling Wang, Thomas J. Lukas, Ming Yuan, Nga Du, Mark O. Tso, Arthur H. Neufeld

published 08 Jan 2009

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Multifactor Effects and Evidence of Potential Interaction between Complement Factor H Y402H and LOC387715 A69S in Age-Related Macular Degeneration

Sanna P. Seitsonen, Päivi Onkamo, Gang Peng, Momiao Xiong, Petri V. Tommila, Päivi H. Ranta, Juha M. Holopainen, Jukka A. Moilanen, Tapani Palosaari, Kai Kaarniranta, Seppo Meri, Ilkka R. Immonen, Irma E. Järvelä

published 02 Dec 2008

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Evaluation of Clustering and Genotype Distribution for Replication in Genome Wide Association Studies: The Age-Related Eye Disease Study

Albert O. Edwards, Brooke L. Fridley, Katherine M. James, Anil S. Sharma, Julie M. Cunningham, Nirubol Tosakulwong

published 26 Nov 2008

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Chronic Cigarette Smoke Causes Oxidative Damage and Apoptosis to Retinal Pigmented Epithelial Cells in Mice

Masashi Fujihara, Norihiro Nagai, Thomas E. Sussan, Shyam Biswal, James T. Handa

published 01 Sep 2008

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Systemic Complement Activation in Age-Related Macular Degeneration

Hendrik P. N. Scholl, Peter Charbel Issa, Maja Walier, Stefanie Janzer, Beatrix Pollok-Kopp, Florian Börncke, Lars G. Fritsche, Ngaihang V. Chong, Rolf Fimmers, Thomas Wienker, Frank G. Holz, Bernhard H. F. Weber, Martin Oppermann

published 02 Jul 2008

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Density of Common Complex Ocular Traits in the Aging Eye: Analysis of Secondary Traits in Genome-Wide Association Studies

Albert O. Edwards, Sung J. Lee, Brooke L. Fridley, Nirubol Tosakulwong

published 25 Jun 2008

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