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Geriatric ophthalmology

A Common Complement C3 Variant Is Associated with Protection against Wet Age-Related Macular Degeneration in a Japanese Population

Suiho Yanagisawa, Naoshi Kondo, Akiko Miki, Wataru Matsumiya, Sentaro Kusuhara, Yasutomo Tsukahara, Shigeru Honda, Akira Negi

published 12 Dec 2011

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Gene Transfer Using Micellar Nanovectors Inhibits Choroidal Neovascularization In Vivo

Aya Iriyama, Makoto Oba, Takehiko Ishii, Nobuhiro Nishiyama, Kazunori Kataoka, Yasuhiro Tamaki, Yasuo Yanagi

published 05 Dec 2011

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Characterisation of a C1qtnf5 Ser163Arg Knock-In Mouse Model of Late-Onset Retinal Macular Degeneration

Xinhua Shu, Ulrich F. O. Luhmann, Tomas S. Aleman, Susan E. Barker, Alan Lennon, Brian Tulloch, Mei Chen, Heping Xu, Samuel G. Jacobson, Robin Ali, Alan F. Wright

published 16 Nov 2011

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A 32 kb Critical Region Excluding Y402H in CFH Mediates Risk for Age-Related Macular Degeneration

Theru A. Sivakumaran, Robert P. Igo Jr, Jeffrey M. Kidd, Andy Itsara, Laura J. Kopplin, Wei Chen, Stephanie A. Hagstrom, Neal S. Peachey, Peter J. Francis, Michael L. Klein, Emily Y. Chew, Vedam L. Ramprasad, Wan-Ting Tay, Paul Mitchell, Mark Seielstad, Dwight E. Stambolian, Albert O. Edwards, Kristine E. Lee, Dmitry V. Leontiev, Gyungah Jun, Yang Wang, Liping Tian, Feiyou Qiu, Alice K. Henning, Thomas LaFramboise, Parveen Sen, Manoharan Aarthi, Ronnie George, Rajiv Raman, Manmath Kumar Das, Lingam Vijaya, Govindasamy Kumaramanickavel, Tien Y. Wong, Anand Swaroop, Goncalo R. Abecasis, Ronald Klein, Barbara E. K. Klein, Deborah A. Nickerson, Evan E. Eichler, Sudha K. Iyengar

published 12 Oct 2011

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Influence of ROBO1 and RORA on Risk of Age-Related Macular Degeneration Reveals Genetically Distinct Phenotypes in Disease Pathophysiology

Gyungah Jun, Michael Nicolaou, Margaux A. Morrison, Jacqueline Buros, Denise J. Morgan, Monte J. Radeke, Yoshihiro Yonekawa, Evangelia E. Tsironi, Maria G. Kotoula, Fani Zacharaki, Nissa Mollema, Yang Yuan, Joan W. Miller, Neena B. Haider, Gregory S. Hageman, Ivana K. Kim, Debra A. Schaumberg, Lindsay A. Farrer, Margaret M. DeAngelis

published 06 Oct 2011

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Dysregulation in Retinal Para-Inflammation and Age-Related Retinal Degeneration in CCL2 or CCR2 Deficient Mice

Mei Chen, John V. Forrester, Heping Xu

published 05 Aug 2011

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Overexpression of HTRA1 Leads to Ultrastructural Changes in the Elastic Layer of Bruch's Membrane via Cleavage of Extracellular Matrix Components

Sarah Vierkotten, Philipp S. Muether, Sascha Fauser

published 02 Aug 2011

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Orally Active Multi-Functional Antioxidants Are Neuroprotective in a Rat Model of Light-Induced Retinal Damage

James Randazzo, Zifeng Zhang, Michael Hoff, Hiroyoshi Kawada, Andrew Sachs, Yang Yuan, Neena Haider, Peter Kador

published 14 Jul 2011

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The Effect of Viewing Eccentricity on Enumeration

Melanie Palomares, Paul R. Smith, Carole Holley Pitts, Breana M. Carter

published 10 Jun 2011

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A Non Membrane-Targeted Human Soluble CD59 Attenuates Choroidal Neovascularization in a Model of Age Related Macular Degeneration

Siobhan M. Cashman, Kasmir Ramo, Rajendra Kumar-Singh

published 28 Apr 2011

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Association between the SERPING1 Gene and Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in Japanese

Isao Nakata, Kenji Yamashiro, Ryo Yamada, Norimoto Gotoh, Hideo Nakanishi, Hisako Hayashi, Akitaka Tsujikawa, Atsushi Otani, Masaaki Saito, Tomohiro Iida, Akio Oishi, Keitaro Matsuo, Kazuo Tajima, Fumihiko Matsuda, Nagahisa Yoshimura

published 19 Apr 2011

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Using Genetic Variation and Environmental Risk Factor Data to Identify Individuals at High Risk for Age-Related Macular Degeneration

Kylee L. Spencer, Lana M. Olson, Nathalie Schnetz-Boutaud, Paul Gallins, Anita Agarwal, Alessandro Iannaccone, Stephen B. Kritchevsky, Melissa Garcia, Michael A. Nalls, Anne B. Newman, William K. Scott, Margaret A. Pericak-Vance, Jonathan L. Haines

published 24 Mar 2011

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Cigarette Smoke-Related Hydroquinone Dysregulates MCP-1, VEGF and PEDF Expression in Retinal Pigment Epithelium in Vitro and in Vivo

Marianne Pons, Maria E. Marin-Castaño

published 28 Feb 2011

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