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Genome engineering

CRISPR-Cas9 In Situ engineering of subtilisin E in Bacillus subtilis

Marcus A. Price, Rita Cruz, Scott Baxter, Franck Escalettes, Susan J. Rosser

published 07 Jan 2019

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Deep learning image recognition enables efficient genome editing in zebrafish by automated injections

Maria Lorena Cordero-Maldonado, Simon Perathoner, Kees-Jan van der Kolk, Ralf Boland, Ursula Heins-Marroquin, Herman P. Spaink, Annemarie H. Meijer, Alexander D. Crawford, Jan de Sonneville

published 07 Jan 2019

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Establishment of a conditional TALEN system using the translational enhancer dMac3 and an inducible promoter activated by glucocorticoid treatment to increase the frequency of targeted mutagenesis in plants

Hitomi Onodera, Saeko Shingu, Mariko Ohnuma, Takaaki Horie, Miho Kihira, Hiroaki Kusano, Hiroshi Teramura, Hiroaki Shimada

published 26 Dec 2018

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Phenotypic and genomic analyses of bacteriophages targeting environmental and clinical CS3-expressing enterotoxigenic Escherichia coli (ETEC) strains

Sajib Chakraborty, Astrid von Mentzer, Yasmin Ara Begum, Mehnaz Manzur, Mahmudul Hasan, Amar N. Ghosh, M. Anwar Hossain, Andrew Camilli, Firdausi Qadri

published 20 Dec 2018

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A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children’s Oncology Group study

Amy E. Armstrong, Samantha Gadd, Vicki Huff, Daniela S. Gerhard, Jeffrey S. Dome, Elizabeth J. Perlman

published 13 Dec 2018

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CBF-dependent and CBF-independent regulatory pathways contribute to the differences in freezing tolerance and cold-regulated gene expression of two Arabidopsis ecotypes locally adapted to sites in Sweden and Italy

Sunchung Park, Sarah J. Gilmour, Rebecca Grumet, Michael F. Thomashow

published 05 Dec 2018

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Deletion of Pr72 causes cardiac developmental defects in Zebrafish

Guibo Song, Mingjun Han, Zuhua Li, Xuedong Gan, Xiaowen Chen, Jie Yang, Sufang Dong, Ming Yan, Jun Wan, Yanggan Wang, Zhuliang Huang, Zhan Yin, Fang Zheng

published 27 Nov 2018

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Efficient CRISPR/Cas9-based genome editing and its application to conditional genetic analysis in Marchantia polymorpha

Shigeo S. Sugano, Ryuichi Nishihama, Makoto Shirakawa, Junpei Takagi, Yoriko Matsuda, Sakiko Ishida, Tomoo Shimada, Ikuko Hara-Nishimura, Keishi Osakabe, Takayuki Kohchi

published 31 Oct 2018

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Accumulation of uric acid in the epidermis forms the white integument of Samia ricini larvae

Jung Lee, Takashi Kiuchi, Munetaka Kawamoto, Toru Shimada, Susumu Katsuma

published 15 Oct 2018

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CRISPR deletion of MIEN1 in breast cancer cells

Timothy Van Treuren, Jamboor K. Vishwanatha

published 04 Oct 2018

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CRISPR/Cas9 engineering of a KIM-1 reporter human proximal tubule cell line

Ruth Ann Veach, Matthew H. Wilson

published 27 Sep 2018

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Pre-existing technological core and roots for the CRISPR breakthrough

Christopher L. Magee, Patrick W. Kleyn, Brendan M. Monks, Ulrich Betz, Subarna Basnet

published 19 Sep 2018

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Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays

Morito Kurata, Natalie K. Wolf, Walker S. Lahr, Madison T. Weg, Mitchell G. Kluesner, Samantha Lee, Kai Hui, Masano Shiraiwa, Beau R. Webber, Branden S. Moriarity

published 17 Sep 2018

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