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Genome engineering

Analysis of Zobellella denitrificans ZD1 draft genome: Genes and gene clusters responsible for high polyhydroxybutyrate (PHB) production from glycerol under saline conditions and its CRISPR-Cas system

Yu-Wei Wu, Shih-Hung Yang, Myung Hwangbo, Kung-Hui Chu

published 12 Sep 2019

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CRISPR-Cas9 mediated CD133 knockout inhibits colon cancer invasion through reduced epithelial-mesenchymal transition

Wanlu Li, Mee-Yon Cho, Suji Lee, Mirae Jang, Junsoo Park, Rackhyun Park

published 08 Aug 2019

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TET1 is an important transcriptional activator of TNFα expression in macrophages

Fangfang Sun, Irene Abreu-Rodriguez, Shuang Ye, Steffen Gay, Oliver Distler, Michel Neidhart, Emmanuel Karouzakis

published 19 Jun 2019

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Splice donor site sgRNAs enhance CRISPR/Cas9-mediated knockout efficiency

Ignacio García-Tuñón, Verónica Alonso-Pérez, Elena Vuelta, Sandra Pérez- Ramos, María Herrero, Lucía Méndez, Jesús María Hernández-Sánchez, Marta Martín-Izquierdo, Raquel Saldaña, Julián Sevilla, Fermín Sánchez- Guijo, Jesús María Hernández-Rivas, Manuel Sánchez-Martín

published 09 May 2019

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Genetic characterisation of variants of the virulence plasmid, pSLT, in Salmonella enterica serovar Typhimurium provides evidence of a variety of evolutionary directions consistent with vertical rather than horizontal transmission

Lester Hiley, Rikki M. A. Graham, Amy V. Jennison

published 11 Apr 2019

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Comparison of efficiency and specificity of CRISPR-associated (Cas) nucleases in plants: An expanded toolkit for precision genome engineering

Oleg Raitskin, Christian Schudoma, Anthony West, Nicola J. Patron

published 27 Feb 2019

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CRISPR-cas gene-editing as plausible treatment of neuromuscular and nucleotide-repeat-expansion diseases: A systematic review

Haris Babačić, Aditi Mehta, Olivia Merkel, Benedikt Schoser

published 22 Feb 2019

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Generation of TGFBI knockout ABCG2+/ABCB5+ double-positive limbal epithelial stem cells by CRISPR/Cas9-mediated genome editing

Eung Kweon Kim, Seunghyuk Kim, Yong-Sun Maeng

published 12 Feb 2019

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Reducing phenolic off-flavors through CRISPR-based gene editing of the FDC1 gene in Saccharomyces cerevisiae x Saccharomyces eubayanus hybrid lager beer yeasts

Stijn Mertens, Brigida Gallone, Jan Steensels, Beatriz Herrera-Malaver, Jeroen Cortebeek, Robbe Nolmans, Veerle Saels, Valmik K. Vyas, Kevin J. Verstrepen

published 09 Jan 2019

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Optimization of T-DNA architecture for Cas9-mediated mutagenesis in Arabidopsis

Baptiste Castel, Laurence Tomlinson, Federica Locci, Ying Yang, Jonathan D. G. Jones

published 09 Jan 2019

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CRISPR-Cas9 In Situ engineering of subtilisin E in Bacillus subtilis

Marcus A. Price, Rita Cruz, Scott Baxter, Franck Escalettes, Susan J. Rosser

published 07 Jan 2019

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Deep learning image recognition enables efficient genome editing in zebrafish by automated injections

Maria Lorena Cordero-Maldonado, Simon Perathoner, Kees-Jan van der Kolk, Ralf Boland, Ursula Heins-Marroquin, Herman P. Spaink, Annemarie H. Meijer, Alexander D. Crawford, Jan de Sonneville

published 07 Jan 2019

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Establishment of a conditional TALEN system using the translational enhancer dMac3 and an inducible promoter activated by glucocorticoid treatment to increase the frequency of targeted mutagenesis in plants

Hitomi Onodera, Saeko Shingu, Mariko Ohnuma, Takaaki Horie, Miho Kihira, Hiroaki Kusano, Hiroshi Teramura, Hiroaki Shimada

published 26 Dec 2018

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