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Genome engineering

CRISPR-mediated accelerated domestication of African rice landraces

Elia Lacchini, Edward Kiegle, Marco Castellani, Hélène Adam, Stefan Jouannic, Veronica Gregis, Martin M. Kater

published 03 Mar 2020

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Are the current gRNA ranking prediction algorithms useful for genome editing in plants?

Fatima Naim, Kylie Shand, Satomi Hayashi, Martin O’Brien, James McGree, Alexander A. T. Johnson, Benjamin Dugdale, Peter M. Waterhouse

published 24 Jan 2020

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Challenges associated with homologous directed repair using CRISPR-Cas9 and TALEN to edit the DMD genetic mutation in canine Duchenne muscular dystrophy

Sara Mata López, Cynthia Balog-Alvarez, Stanislav Vitha, Amanda K. Bettis, Emily H. Canessa, Joe N. Kornegay, Peter P. Nghiem

published 21 Jan 2020

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AlleleProfileR: A versatile tool to identify and profile sequence variants in edited genomes

Arne A. N. Bruyneel, Alexandre R. Colas, Ioannis Karakikes, Mark Mercola

published 26 Dec 2019

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High throughput, efficacious gene editing & genome surveillance in Chinese hamster ovary cells

S. C. Huhn, Y. Ou, A. Kumar, R. Liu, Z. Du

published 19 Dec 2019

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A single plasmid based CRISPR interference in Synechocystis 6803 – A proof of concept

Prithwiraj Kirtania, Barbara Hódi, Ivy Mallick, István Zoltan Vass, Tamás Fehér, Imre Vass, Peter B. Kós

published 26 Nov 2019

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CRISPR-Cas influences the acquisition of antibiotic resistance in Klebsiella pneumoniae

Natalie A. Mackow, Juntao Shen, Mutayyaba Adnan, Aisha S. Khan, Bettina C. Fries, Elizabeth Diago-Navarro

published 20 Nov 2019

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Genomic comparison of diverse Salmonella serovars isolated from swine

Sushim K. Gupta, Poonam Sharma, Elizabeth A. McMillan, Charlene R. Jackson, Lari M. Hiott, Tiffanie Woodley, Shaheen B. Humayoun, John B. Barrett, Jonathan G. Frye, Michael McClelland

published 01 Nov 2019

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Off-target effects of CRISPRa on interleukin-6 expression

Sébastien Soubeyrand, Paulina Lau, Victoria Peters, Ruth McPherson

published 28 Oct 2019

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Multiplexed editing of a begomovirus genome restricts escape mutant formation and disease development

Anirban Roy, Ying Zhai, Jessica Ortiz, Michael Neff, Bikash Mandal, Sunil Kumar Mukherjee, Hanu R. Pappu

published 23 Oct 2019

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Generation of deletions and precise point mutations in Dictyostelium discoideum using the CRISPR nickase

Hoshie Iriki, Takefumi Kawata, Tetsuya Muramoto

published 17 Oct 2019

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Gene editing of PKLR gene in human hematopoietic progenitors through 5’ and 3’ UTR modified TALEN mRNA

Oscar Quintana-Bustamante, Sara Fañanas-Baquero, Israel Orman, Raul Torres, Philippe Duchateau, Laurent Poirot, Agnès Gouble, Juan A. Bueren, Jose C. Segovia

published 16 Oct 2019

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Integration of a FT expression cassette into CRISPR/Cas9 construct enables fast generation and easy identification of transgene-free mutants in Arabidopsis

Yuxin Cheng, Na Zhang, Saddam Hussain, Sajjad Ahmed, Wenting Yang, Shucai Wang

published 23 Sep 2019

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