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Genome engineering

Gene knock-outs in human CD34+ hematopoietic stem and progenitor cells and in the human immune system of mice

Daniel A. Kuppers, Jonathan Linton, [ ... ], Patrick J. Paddison

The structure of a Type III-A CRISPR-Cas effector complex reveals conserved and idiosyncratic contacts to target RNA and crRNA among Type III-A systems

Mohammadreza Paraan, Mohamed Nasef, [ ... ], Jack A. Dunkle

Targeted deletion of grape retrotransposon associated with fruit skin color via CRISPR/Cas9 in Vitis labrascana ‘Shine Muscat’

Ikuko Nakajima, Hiroyuki Kawahigashi, [ ... ], Masaki Endo

Optimization of gene editing in cowpea through protoplast transformation and agroinfiltration by targeting the phytoene desaturase gene

Aya Bridgeland, Sudip Biswas, [ ... ], Endang M. Septiningsih

Small-molecule inhibitors of proteasome increase CjCas9 protein stability

Pouiré Yaméogo, Nathalie Majeau, Cedric Happi Mbakam, Jacques P. Tremblay

The CRISPR genotypes and genetic diversity of different serogroups of nontyphoidal Salmonella in Guizhou Province, 2013–2018

Guihuan Bai, Lv You, [ ... ], Shijun Li

Consumer acceptance of new plant-breeding technologies: An application to the use of gene editing in fresh table grapes

Azhar Uddin, R. Karina Gallardo, [ ... ], Olena Sambucci

Diagnostic efficiency of RPA/RAA integrated CRISPR-Cas technique for COVID-19: A systematic review and meta-analysis

Xiaoyu Zhang, Xiao Ge, [ ... ], Heng Li

Genomic comparison of Planktothrix agardhii isolates from a Lake Erie embayment

Katelyn M. McKindles, R. Michael McKay, George S. Bullerjahn

A precise gene delivery approach for human induced pluripotent stem cells using Cas9 RNP complex and recombinant AAV6 donor vectors

Koollawat Chupradit, Nontaphat Thongsin, Chatchai Tayapiwatana, Methichit Wattanapanitch

CRISPR/Cas9-mediated targeted mutagenesis of GmTCP19L increasing susceptibility to Phytophthora sojae in soybean

Sujie Fan, Zhuo Zhang, [ ... ], Piwu Wang

Genome editing using preassembled CRISPR-Cas9 ribonucleoprotein complexes in Fusarium graminearum

Nahyun Lee, Jiyeun Park, [ ... ], Hokyoung Son

A programmable DNA roadblock system using dCas9 and multivalent target sites

Emily K. Matozel, Stephen Parziale, Allen C. Price

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