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Genome engineering

Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs)

Finola E. Moore, Deepak Reyon, Jeffry D. Sander, Sarah A. Martinez, Jessica S. Blackburn, Cyd Khayter, Cherie L. Ramirez, J. Keith Joung, David M. Langenau

published 24 May 2012

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CRISPR Typing and Subtyping for Improved Laboratory Surveillance of Salmonella Infections

Laëtitia Fabre, Jian Zhang, Ghislaine Guigon, Simon Le Hello, Véronique Guibert, Marie Accou-Demartin, Saïana de Romans, Catherine Lim, Chrystelle Roux, Virginie Passet, Laure Diancourt, Martine Guibourdenche, Sylvie Issenhuth-Jeanjean, Mark Achtman, Sylvain Brisse, Christophe Sola, François-Xavier Weill

published 18 May 2012

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Stable Gene Targeting in Human Cells Using Single-Strand Oligonucleotides with Modified Bases

Xavier Rios, Adrian W. Briggs, Danos Christodoulou, Josh M. Gorham, Jonathan G. Seidman, George M. Church

published 14 May 2012

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CRISPR Interference Directs Strand Specific Spacer Acquisition

Daan C. Swarts, Cas Mosterd, Mark W. J. van Passel, Stan J. J. Brouns

published 27 Apr 2012

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Synthetic Biology: Mapping the Scientific Landscape

Paul Oldham, Stephen Hall, Geoff Burton

published 23 Apr 2012

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CRISPR/cas Loci of Type II Propionibacterium acnes Confer Immunity against Acquisition of Mobile Elements Present in Type I P. acnes

Holger Brüggemann, Hans B. Lomholt, Hervé Tettelin, Mogens Kilian

published 30 Mar 2012

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Reconstructing Viral Genomes from the Environment Using Fosmid Clones: The Case of Haloviruses

Inmaculada Garcia-Heredia, Ana-Belen Martin-Cuadrado, Francisco J. M. Mojica, Fernando Santos, Alex Mira, Josefa Antón, Francisco Rodriguez-Valera

published 30 Mar 2012

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Crystal Structure of Streptococcus pyogenes Csn2 Reveals Calcium-Dependent Conformational Changes in Its Tertiary and Quaternary Structure

Yoon Koo, Du-kyo Jung, Euiyoung Bae

published 30 Mar 2012

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Yersinia pestis Lineages in Mongolia

Julia M. Riehm, Gilles Vergnaud, Daniel Kiefer, Tserennorov Damdindorj, Otgonbaatar Dashdavaa, Tungalag Khurelsukh, Lothar Zöller, Roman Wölfel, Philippe Le Flèche, Holger C. Scholz

published 17 Feb 2012

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Selection-Independent Generation of Gene Knockout Mouse Embryonic Stem Cells Using Zinc-Finger Nucleases

Anna Osiak, Frank Radecke, Eva Guhl, Sarah Radecke, Nadine Dannemann, Fabienne Lütge, Silke Glage, Cornelia Rudolph, Tobias Cantz, Klaus Schwarz, Regine Heilbronn, Toni Cathomen

published 14 Dec 2011

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Heritable Targeted Inactivation of Myostatin Gene in Yellow Catfish (Pelteobagrus fulvidraco) Using Engineered Zinc Finger Nucleases

Zhangji Dong, Jiachun Ge, Kui Li, Zhiqiang Xu, Dong Liang, Jingyun Li, Junbo Li, Wenshuang Jia, Yuehua Li, Xiaohua Dong, Shasha Cao, Xiaoxiao Wang, Jianlin Pan, Qingshun Zhao

published 14 Dec 2011

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Haloquadratum walsbyi : Limited Diversity in a Global Pond

Mike L. Dyall-Smith, Friedhelm Pfeiffer, Kathrin Klee, Peter Palm, Karin Gross, Stephan C. Schuster, Markus Rampp, Dieter Oesterhelt

published 20 Jun 2011

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Efficient Immunoglobulin Gene Disruption and Targeted Replacement in Rabbit Using Zinc Finger Nucleases

Tatiana Flisikowska, Irmgard S. Thorey, Sonja Offner, Francesca Ros, Valeria Lifke, Bryan Zeitler, Oswald Rottmann, Anna Vincent, Lei Zhang, Shirin Jenkins, Helmut Niersbach, Alexander J. Kind, Philip D. Gregory, Angelika E. Schnieke, Josef Platzer

published 13 Jun 2011

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