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Genome engineering

Target Motifs Affecting Natural Immunity by a Constitutive CRISPR-Cas System in Escherichia coli

Cristóbal Almendros, Noemí M. Guzmán, César Díez-Villaseñor, Jesús García-Martínez, Francisco J. M. Mojica

published 26 Nov 2012

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Targeted Genomic Integration of a Selectable Floxed Dual Fluorescence Reporter in Human Embryonic Stem Cells

Jay A. Gantz, Nathan J. Palpant, Robert E. Welikson, Stephen D. Hauschka, Charles E. Murry, Michael A. Laflamme

published 10 Oct 2012

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The CRISPR Associated Protein Cas4 Is a 5′ to 3′ DNA Exonuclease with an Iron-Sulfur Cluster

Jing Zhang, Taciana Kasciukovic, Malcolm F. White

published 08 Oct 2012

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Targeting G with TAL Effectors: A Comparison of Activities of TALENs Constructed with NN and NK Repeat Variable Di-Residues

Michelle L. Christian, Zachary L. Demorest, Colby G. Starker, Mark J. Osborn, Michael D. Nyquist, Yong Zhang, Daniel F. Carlson, Philip Bradley, Adam J. Bogdanove, Daniel F. Voytas

published 24 Sep 2012

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Rescue the Failed Half-ZFN by a Sensitive Mammalian Cell-Based Luciferase Reporter System

Weifeng Zhang, Yuanxu Guo, Chen Zhang, Haiyan Ji, Wenpeng Meng, Dongyang Wang, Xing Li, Qinwen Mao, Haibin Xia

published 18 Sep 2012

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Highly Efficient and Specific Genome Editing in Silkworm Using Custom TALENs

Sanyuan Ma, Shengling Zhang, Feng Wang, Yong Liu, Yuanyuan Liu, Hanfu Xu, Chun Liu, Ying Lin, Ping Zhao, Qingyou Xia

published 18 Sep 2012

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Diversity of Acinetobacter baumannii in Four French Military Hospitals, as Assessed by Multiple Locus Variable Number of Tandem Repeats Analysis

Yolande Hauck, Charles Soler, Patrick Jault, Audrey Mérens, Patrick Gérome, Christine Mac Nab, François Trueba, Laurent Bargues, Hoang Vu Thien, Gilles Vergnaud, Christine Pourcel

published 12 Sep 2012

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Evaluation of OPEN Zinc Finger Nucleases for Direct Gene Targeting of the ROSA26 Locus in Mouse Embryos

Mario Hermann, Morgan L. Maeder, Kyle Rector, Joseph Ruiz, Burkhard Becher, Kurt Bürki, Cyd Khayter, Adriano Aguzzi, J. Keith Joung, Thorsten Buch, Pawel Pelczar

published 06 Sep 2012

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Zebrafish foxP2 Zinc Finger Nuclease Mutant Has Normal Axon Pathfinding

Lingyan Xing, Kazuyuki Hoshijima, David J. Grunwald, Esther Fujimoto, Tyler S. Quist, Jacob Sneddon, Chi-Bin Chien, Tamara J. Stevenson, Joshua L. Bonkowsky

published 24 Aug 2012

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Erwinia amylovora CRISPR Elements Provide New Tools for Evaluating Strain Diversity and for Microbial Source Tracking

Gayle C. McGhee, George W. Sundin

published 31 Jul 2012

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Sequencing of Seven Haloarchaeal Genomes Reveals Patterns of Genomic Flux

Erin A. Lynch, Morgan G. I. Langille, Aaron Darling, Elizabeth G. Wilbanks, Caitlin Haltiner, Katie S. Y. Shao, Michael O. Starr, Clotilde Teiling, Timothy T. Harkins, Robert A. Edwards, Jonathan A. Eisen, Marc T. Facciotti

published 24 Jul 2012

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Cleavage of Phage DNA by the Streptococcus thermophilus CRISPR3-Cas System

Alfonso H. Magadán, Marie-Ève Dupuis, Manuela Villion, Sylvain Moineau

published 20 Jul 2012

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Phage-Induced Expression of CRISPR-Associated Proteins Is Revealed by Shotgun Proteomics in Streptococcus thermophilus

Jacque C. Young, Brian D. Dill, Chongle Pan, Robert L. Hettich, Jillian F. Banfield, Manesh Shah, Christophe Fremaux, Philippe Horvath, Rodolphe Barrangou, Nathan C. VerBerkmoes

published 30 May 2012

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