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Genome engineering

Genomic features of “Candidatus Venteria ishoeyi”, a new sulfur-oxidizing macrobacterium from the Humboldt Sulfuretum off Chile

Alexis Fonseca, Thomas Ishoey, [ ... ], Víctor A. Gallardo

Ares-GT: Design of guide RNAs targeting multiple genes for CRISPR-Cas experiments

Eugenio Gómez Minguet

GO-CRISPR: A highly controlled workflow to discover gene essentiality in loss-of-function screens

Pirunthan Perampalam, James I. McDonald, Frederick A. Dick

A Novel Genetic System Based on Zinc Finger Nucleases for the Identification of Interactions between Proteins In Vivo

Ling Wang, Kun Xu, [ ... ], Zhiying Zhang

Reversible perturbations of gene regulation after genome editing in Drosophila cells

Stefan Kunzelmann, Klaus Förstemann

Comparative evaluation of bioinformatic tools for virus-host prediction and their application to a highly diverse community in the Cuatro Ciénegas Basin, Mexico

Alejandro Miguel Cisneros-Martínez, Ulises E. Rodriguez-Cruz, [ ... ], Valeria Souza

Rescue the Failed Half-ZFN by a Sensitive Mammalian Cell-Based Luciferase Reporter System

Weifeng Zhang, Yuanxu Guo, [ ... ], Haibin Xia

Genomic diversity of Taylorella equigenitalis introduced into the United States from 1978 to 2012

Jessica Hicks, Tod Stuber, [ ... ], Xiaoqiu Huang

An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells

Marek J. Kobylarz, Jonathan M. Goodwin, [ ... ], Beat Nyfeler

The structure of a Type III-A CRISPR-Cas effector complex reveals conserved and idiosyncratic contacts to target RNA and crRNA among Type III-A systems

Mohammadreza Paraan, Mohamed Nasef, [ ... ], Jack A. Dunkle

Enhanced Rb/E2F and TSC/mTOR Pathways Induce Synergistic Inhibition in PDGF-Induced Proliferation in Vascular Smooth Muscle Cells

Yue Li, Xuan Li, [ ... ], Jianchang Wang

Rats deficient C-type natriuretic peptide suffer from impaired skeletal growth without early death

Toshihito Fujii, Keisho Hirota, [ ... ], Kazuwa Nakao

SplitAx: A novel method to assess the function of engineered nucleases

Richard A. Axton, Sharmin S. Haideri, [ ... ], Lesley M. Forrester

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