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Genome engineering

Inheritable and Precise Large Genomic Deletions of Non-Coding RNA Genes in Zebrafish Using TALENs

Yun Liu, Daji Luo, Hui Zhao, Zuoyan Zhu, Wei Hu, Christopher H. K. Cheng

published 10 Oct 2013

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Generation of Interleukin-2 Receptor Gamma Gene Knockout Pigs from Somatic Cells Genetically Modified by Zinc Finger Nuclease-Encoding mRNA

Masahito Watanabe, Kazuaki Nakano, Hitomi Matsunari, Taisuke Matsuda, Miki Maehara, Takahiro Kanai, Mirina Kobayashi, Yukina Matsumura, Rieko Sakai, Momoko Kuramoto, Gota Hayashida, Yoshinori Asano, Shuko Takayanagi, Yoshikazu Arai, Kazuhiro Umeyama, Masaki Nagaya, Yutaka Hanazono, Hiroshi Nagashima

published 09 Oct 2013

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RNA-Seq Reveals Differential Gene Expression in Staphylococcus aureus with Single-Nucleotide Resolution

Joseph Osmundson, Scott Dewell, Seth A. Darst

published 07 Oct 2013

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ULtiMATE System for Rapid Assembly of Customized TAL Effectors

Junjiao Yang, Pengfei Yuan, Dingqiao Wen, Ying Sheng, Shiyou Zhu, Yuezhou Yu, Xiang Gao, Wensheng Wei

published 27 Sep 2013

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Efficient TALEN Construction for Bombyx mori Gene Targeting

Yoko Takasu, Suresh Sajwan, Takaaki Daimon, Mizuko Osanai-Futahashi, Keiro Uchino, Hideki Sezutsu, Toshiki Tamura, Michal Zurovec

published 18 Sep 2013

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Targeted Mutagenesis in the Malaria Mosquito Using TALE Nucleases

Andrea L. Smidler, Olivier Terenzi, Julien Soichot, Elena A. Levashina, Eric Marois

published 15 Aug 2013

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Structure and Genetic Content of the Megaplasmids of Neurotoxigenic Clostridium butyricum Type E Strains from Italy

Angelo Iacobino, Concetta Scalfaro, Giovanna Franciosa

published 15 Aug 2013

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Lactobacillus paracasei Comparative Genomics: Towards Species Pan-Genome Definition and Exploitation of Diversity

Tamara Smokvina, Michiel Wels, Justyna Polka, Christian Chervaux, Sylvain Brisse, Jos Boekhorst, Johan E. T. van Hylckama Vlieg, Roland J. Siezen

published 19 Jul 2013

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Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System

Woong Y. Hwang, Yanfang Fu, Deepak Reyon, Morgan L. Maeder, Prakriti Kaini, Jeffry D. Sander, J. Keith Joung, Randall T. Peterson, Jing-Ruey Joanna Yeh

published 09 Jul 2013

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Tagging of Genomic STAT3 and STAT1 with Fluorescent Proteins and Insertion of a Luciferase Reporter in the Cyclin D1 Gene Provides a Modified A549 Cell Line to Screen for Selective STAT3 Inhibitors

Andrey Samsonov, Nathan Zenser, Fan Zhang, Hongyi Zhang, John Fetter, Dmitry Malkov

published 09 Jul 2013

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A Simple and Efficient Method for Assembling TALE Protein Based on Plasmid Library

Zhiqiang Zhang, Duo Li, Huarong Xu, Ying Xin, Tingting Zhang, Lixia Ma, Xin Wang, Zhilong Chen, Zhiying Zhang

published 20 Jun 2013

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Zinc Finger Nuclease Mediated Knockout of ADP-Dependent Glucokinase in Cancer Cell Lines: Effects on Cell Survival and Mitochondrial Oxidative Metabolism

Susan Richter, Shona Morrison, Tim Connor, Jiechuang Su, Cristin G. Print, Ron S. Ronimus, Sean L. McGee, William R. Wilson

published 14 Jun 2013

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Simultaneous Screening and Validation of Effective Zinc Finger Nucleases in Yeast

Ling Wang, Juan Lin, Tingting Zhang, Kun Xu, Chonghua Ren, Zhiying Zhang

published 31 May 2013

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