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Genome engineering

Cell-Penetrating Peptide-Mediated Delivery of TALEN Proteins via Bioconjugation for Genome Engineering

Jia Liu, Thomas Gaj, James T. Patterson, Shannon J. Sirk, Carlos F. Barbas III

published 20 Jan 2014

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Comparative Genome Analysis of Campylobacter fetus Subspecies Revealed Horizontally Acquired Genetic Elements Important for Virulence and Niche Specificity

Sabine Kienesberger, Hanna Sprenger, Stella Wolfgruber, Bettina Halwachs, Gerhard G. Thallinger, Guillermo I. Perez-Perez, Martin J. Blaser, Ellen L. Zechner, Gregor Gorkiewicz

published 09 Jan 2014

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A Modified TALEN-Based Strategy for Rapidly and Efficiently Generating Knockout Mice for Kidney Development Studies

Yunhong Liu, Xiaoyan Lv, Ruizhi Tan, Tianming Liu, Tielin Chen, Mi Li, Yuhang Liu, Fang Nie, Xiaoyan Wang, Puhui Zhou, Mianzhi Chen, Qin Zhou

published 08 Jan 2014

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A Novel Genetic System Based on Zinc Finger Nucleases for the Identification of Interactions between Proteins In Vivo

Ling Wang, Kun Xu, Juan Lin, Simin Shao, Tingting Zhang, Huarong Xu, Zehui Wei, Zhiying Zhang

published 31 Dec 2013

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Tandem Repeat Modification during Double-Strand Break Repair Induced by an Engineered TAL Effector Nuclease in Zebrafish Genome

Wanxu Huang, Jianbo Zheng, Ying He, Chen Luo

published 26 Dec 2013

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Highly Efficient Generation of GGTA1 Biallelic Knockout Inbred Mini-Pigs with TALENs

Jige Xin, Huaqiang Yang, Nana Fan, Bentian Zhao, Zhen Ouyang, Zhaoming Liu, Yu Zhao, Xiaoping Li, Jun Song, Yi Yang, Qingjian Zou, Quanmei Yan, Yangzhi Zeng, Liangxue Lai

published 17 Dec 2013

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TALE-PvuII Fusion Proteins – Novel Tools for Gene Targeting

Mert Yanik, Jamal Alzubi, Thomas Lahaye, Toni Cathomen, Alfred Pingoud, Wolfgang Wende

published 05 Dec 2013

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TAL Effector Specificity for base 0 of the DNA Target Is Altered in a Complex, Effector- and Assay-Dependent Manner by Substitutions for the Tryptophan in Cryptic Repeat –1

Erin L. Doyle, Aaron W. Hummel, Zachary L. Demorest, Colby G. Starker, Daniel F. Voytas, Philip Bradley, Adam J. Bogdanove

published 03 Dec 2013

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Functional Analysis of a Breast Cancer-Associated FGFR2 Single Nucleotide Polymorphism Using Zinc Finger Mediated Genome Editing

Luisa J. Robbez-Masson, Csaba Bödör, J. Louise Jones, Helen C. Hurst, Jude Fitzgibbon, Ian R. Hart, Richard P. Grose

published 12 Nov 2013

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Rapid Assembly of Customized TALENs into Multiple Delivery Systems

Zhengxing Zhang, Siliang Zhang, Xin Huang, Kyle E. Orwig, Yi Sheng

published 07 Nov 2013

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An Over Expression APP Model for Anti-Alzheimer Disease Drug Screening Created by Zinc Finger Nuclease Technology

Xiaojing Zhang, Hui Li, Yiqing Mao, Zhixin Li, Rong Wang, Tingting Guo, Ling Jin, Rongjing Song, Wei Xu, Na Zhou, Yizhuang Zhang, Ruobi Hu, Xi Wang, Huakang Huang, Zhen Lei, Gang Niu, David M. Irwin, Huanran Tan

published 06 Nov 2013

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Cultivation and Complete Genome Sequencing of Gloeobacter kilaueensis sp. nov., from a Lava Cave in Kīlauea Caldera, Hawai'i

Jimmy H. W. Saw, Michael Schatz, Mark V. Brown, Dennis D. Kunkel, Jamie S. Foster, Harry Shick, Stephanie Christensen, Shaobin Hou, Xuehua Wan, Stuart P. Donachie

published 23 Oct 2013

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Efficient Knockin Mouse Generation by ssDNA Oligonucleotides and Zinc-Finger Nuclease Assisted Homologous Recombination in Zygotes

Bin Shen, Xin Zhang, Yinan Du, Jianying Wang, Jun Gong, Xiaodong Zhang, Peri H. Tate, Hongliang Li, Xingxu Huang, Wensheng Zhang

published 22 Oct 2013

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