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Genome engineering

Use of Genome Engineering to Create Patient Specific MLL Translocations in Primary Human Hematopoietic Stem and Progenitor Cells

Erin H. Breese, Corina Buechele, [ ... ], Matthew H. Porteus

In silico analysis of potential off-target sites to gene editing for Mucopolysaccharidosis type I using the CRISPR/Cas9 system: Implications for population-specific treatments

Paola Carneiro, Martiela Vaz de Freitas, Ursula Matte

Novel fluorescent-based reporter cell line engineered for monitoring homologous recombination events

Alejandra Bernardi, Dino Gobelli, [ ... ], Miguel A. de la Fuente

Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells

Shinsaku Tokuda, Toyohiro Hirai, Mikio Furuse

Simultaneous Screening and Validation of Effective Zinc Finger Nucleases in Yeast

Ling Wang, Juan Lin, [ ... ], Zhiying Zhang

Multi-Agent Chemotherapy Overcomes Glucocorticoid Resistance Conferred by a BIM Deletion Polymorphism in Pediatric Acute Lymphoblastic Leukemia

Sheila Xinxuan Soh, Joshua Yew Suang Lim, [ ... ], S. Tiong Ong

The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging

Barbara Dupret, Pamela Völkel, Xuefen Le Bourhis, Pierre-Olivier Angrand

Antimicrobial Resistance and Molecular Investigation of H₂S-Negative Salmonella enterica subsp. enterica serovar Choleraesuis Isolates in China

Jing Xie, Shengjie Yi, [ ... ], Hongbin Song

Pre-existing technological core and roots for the CRISPR breakthrough

Christopher L. Magee, Patrick W. Kleyn, [ ... ], Subarna Basnet

Analysis of Zobellella denitrificans ZD1 draft genome: Genes and gene clusters responsible for high polyhydroxybutyrate (PHB) production from glycerol under saline conditions and its CRISPR-Cas system

Yu-Wei Wu, Shih-Hung Yang, Myung Hwangbo, Kung-Hui Chu

Accumulation of uric acid in the epidermis forms the white integument of Samia ricini larvae

Jung Lee, Takashi Kiuchi, [ ... ], Susumu Katsuma

Integration of a FT expression cassette into CRISPR/Cas9 construct enables fast generation and easy identification of transgene-free mutants in Arabidopsis

Yuxin Cheng, Na Zhang, [ ... ], Shucai Wang

Development of an optimized protocol for generating knockout cancer cell lines using the CRISPR/Cas9 system, with emphasis on transient transfection

Seyed Alireza Mousavi Kahaki, Nayereh Ebrahimzadeh, Hossein Fahimi, Arfa Moshiri

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