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Genome engineering

The Effect of Zinc and D-Penicillamine in a Stable Human Hepatoma ATP7B Knockout Cell Line

Gursimran Chandhok, Nadine Schmitt, Vanessa Sauer, Annu Aggarwal, Mohit Bhatt, Hartmut H. J. Schmidt

published 03 Jun 2014

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CRISPR/Cas9-Mediated Phage Resistance Is Not Impeded by the DNA Modifications of Phage T4

Stephanie J. Yaung, Kevin M. Esvelt, George M. Church

published 02 Jun 2014

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AAV-Mediated Delivery of Zinc Finger Nucleases Targeting Hepatitis B Virus Inhibits Active Replication

Nicholas D. Weber, Daniel Stone, Ruth Hall Sedlak, Harshana S. De Silva Feelixge, Pavitra Roychoudhury, Joshua T. Schiffer, Martine Aubert, Keith R. Jerome

published 14 May 2014

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Simple and Efficient Methods for Enrichment and Isolation of Endonuclease Modified Cells

Branden S. Moriarity, Eric P. Rahrmann, Dominic A. Beckmann, Caitlin B. Conboy, Adrienne L. Watson, Daniel F. Carlson, Erik R. Olson, Kendra A. Hyland, Scott C. Fahrenkrug, R. Scott McIvor, David A. Largaespada

published 05 May 2014

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The Position of DNA Cleavage by TALENs and Cell Synchronization Influences the Frequency of Gene Editing Directed by Single-Stranded Oligonucleotides

Natalia Rivera-Torres, Bryan Strouse, Pawel Bialk, Rohina A. Niamat, Eric B. Kmiec

published 01 May 2014

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Highly Specific Contractions of a Single CAG/CTG Trinucleotide Repeat by TALEN in Yeast

Guy-Franck Richard, David Viterbo, Varun Khanna, Valentine Mosbach, Lauriane Castelain, Bernard Dujon

published 18 Apr 2014

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A Simple and Effective Method for Construction of Escherichia coli Strains Proficient for Genome Engineering

Young Shin Ryu, Rajesh Kumar Biswas, Kwangsu Shin, Vinuselvi Parisutham, Suk Min Kim, Sung Kuk Lee

published 18 Apr 2014

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Targeted Genome Editing of Sweet Orange Using Cas9/sgRNA

Hongge Jia, Nian Wang

published 07 Apr 2014

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Precise Gene Modification Mediated by TALEN and Single-Stranded Oligodeoxynucleotides in Human Cells

Xiaoling Wang, Yingjia Wang, He Huang, Buyuan Chen, Xinji Chen, Jianda Hu, Tammy Chang, Ren-Jang Lin, Jiing-Kuan Yee

published 01 Apr 2014

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True-Breeding Targeted Gene Knock-Out in Barley Using Designer TALE-Nuclease in Haploid Cells

Maia Gurushidze, Goetz Hensel, Stefan Hiekel, Sindy Schedel, Vladimir Valkov, Jochen Kumlehn

published 18 Mar 2014

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Bacterial Delivery of TALEN Proteins for Human Genome Editing

Jingyue Jia, Yongxin Jin, Ting Bian, Donghai Wu, Lijun Yang, Naohiro Terada, Weihui Wu, Shouguang Jin

published 11 Mar 2014

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Investigating the Interplay between Nucleoid-Associated Proteins, DNA Curvature, and CRISPR Elements Using Comparative Genomics

Hao Tong, Jan Mrázek

published 03 Mar 2014

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TALEN-Mediated Modification of the Bovine Genome for Large-Scale Production of Human Serum Albumin

Shaida Moghaddassi, Will Eyestone, Colin E. Bishop

published 21 Feb 2014

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