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Genome engineering

Detailed Phenotypic and Molecular Analyses of Genetically Modified Mice Generated by CRISPR-Cas9-Mediated Editing

Bijal A. Parikh, Diana L. Beckman, [ ... ], Wayne M. Yokoyama

Transcription Activator-Like Effector Nuclease (TALEN)-Mediated CLYBL Targeting Enables Enhanced Transgene Expression and One-Step Generation of Dual Reporter Human Induced Pluripotent Stem Cell (iPSC) and Neural Stem Cell (NSC) Lines

Trevor Cerbini, Ray Funahashi, [ ... ], Jizhong Zou

High-Throughput Genome Editing and Phenotyping Facilitated by High Resolution Melting Curve Analysis

Holly R. Thomas, Stefanie M. Percival, Bradley K. Yoder, John M. Parant

CRISPR-Cas9-Based Knockout of the Prion Protein and Its Effect on the Proteome

Mohadeseh Mehrabian, Dylan Brethour, [ ... ], Gerold Schmitt-Ulms

CRISPR Reveals a Distal Super-Enhancer Required for Sox2 Expression in Mouse Embryonic Stem Cells

Yan Li, Chloe M. Rivera, [ ... ], Bing Ren

TALEN/CRISPR-Mediated eGFP Knock-In Add-On at the OCT4 Locus Does Not Impact Differentiation of Human Embryonic Stem Cells towards Endoderm

Nicole A. J. Krentz, Cuilan Nian, Francis C. Lynn

Genome Editing in Mouse Spermatogonial Stem/Progenitor Cells Using Engineered Nucleases

Danielle A. Fanslow, Stacey E. Wirt, [ ... ], Christina Tenenhaus Dann

Evaluation of sgRNA Target Sites for CRISPR-Mediated Repression of TP53

Ingrid E. B. Lawhorn, Joshua P. Ferreira, Clifford L. Wang

Antibody-Free Magnetic Cell Sorting of Genetically Modified Primary Human CD4+ T Cells by One-Step Streptavidin Affinity Purification

Nicholas J. Matheson, Andrew A. Peden, Paul J. Lehner

MacSyFinder: A Program to Mine Genomes for Molecular Systems with an Application to CRISPR-Cas Systems

Sophie S. Abby, Bertrand Néron, [ ... ], Eduardo P. C. Rocha

Genome Analysis of Environmental and Clinical P. aeruginosa Isolates from Sequence Type-1146

David Sánchez, Margarita Gomila, [ ... ], Elena García-Valdés

Dynamics of CRISPR Loci in Microevolutionary Process of Yersinia pestis Strains

Maria Paloma S. Barros, Camila T. França, [ ... ], Tereza Cristina Leal-Balbino

Targeted Mutagenesis in Atlantic Salmon (Salmo salar L.) Using the CRISPR/Cas9 System Induces Complete Knockout Individuals in the F0 Generation

Rolf B. Edvardsen, Sven Leininger, [ ... ], Anna Wargelius

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