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Genome engineering

Occurrence and Diversity of CRISPR-Cas Systems in the Genus Bifidobacterium

Alexandra E. Briner, Gabriele Andrea Lugli, Christian Milani, Sabrina Duranti, Francesca Turroni, Miguel Gueimonde, Abelardo Margolles, Douwe van Sinderen, Marco Ventura, Rodolphe Barrangou

published 31 Jul 2015

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Efficient fdCas9 Synthetic Endonuclease with Improved Specificity for Precise Genome Engineering

Mustapha Aouida, Ayman Eid, Zahir Ali, Thomas Cradick, Ciaran Lee, Harshavardhan Deshmukh, Ahmed Atef, Dina AbuSamra, Samah Zeineb Gadhoum, Jasmeen Merzaban, Gang Bao, Magdy Mahfouz

published 30 Jul 2015

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A TALEN-Exon Skipping Design for a Bethlem Myopathy Model in Zebrafish

Zlatko Radev, Jean-Michel Hermel, Yannick Elipot, Sandrine Bretaud, Sylvain Arnould, Philippe Duchateau, Florence Ruggiero, Jean-Stéphane Joly, Frédéric Sohm

published 29 Jul 2015

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CRISPR/Cas9-Mediated Genomic Deletion of the Beta-1, 4 N-acetylgalactosaminyltransferase 1 Gene in Murine P19 Embryonal Carcinoma Cells Results in Low Sensitivity to Botulinum Neurotoxin Type C

Kentaro Tsukamoto, Chikako Ozeki, Tomoko Kohda, Takao Tsuji

published 15 Jul 2015

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Genomics and Machine Learning for Taxonomy Consensus: The Mycobacterium tuberculosis Complex Paradigm

Jérôme Azé, Christophe Sola, Jian Zhang, Florian Lafosse-Marin, Memona Yasmin, Rubina Siddiqui, Kristin Kremer, Dick van Soolingen, Guislaine Refrégier

published 08 Jul 2015

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CRISPR Content Correlates with the Pathogenic Potential of Escherichia coli

Enriqueta García-Gutiérrez, Cristóbal Almendros, Francisco J. M. Mojica, Noemí M. Guzmán, Jesús García-Martínez

published 02 Jul 2015

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Thymosin Beta-4 Induces Mouse Hair Growth

Xiaoyu Gao, Hao Liang, Fang Hou, Zhipeng Zhang, Mingtu Nuo, Xudong Guo, Dongjun Liu

published 17 Jun 2015

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Pervasive Genotypic Mosaicism in Founder Mice Derived from Genome Editing through Pronuclear Injection

Daniel Oliver, Shuiqiao Yuan, Hayden McSwiggin, Wei Yan

published 08 Jun 2015

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Regulation of Gene Editing Activity Directed by Single-Stranded Oligonucleotides and CRISPR/Cas9 Systems

Pawel Bialk, Natalia Rivera-Torres, Bryan Strouse, Eric B. Kmiec

published 08 Jun 2015

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Efficient Multiple Genome Modifications Induced by the crRNAs, tracrRNA and Cas9 Protein Complex in Zebrafish

Hirohito Kotani, Kiyohito Taimatsu, Rie Ohga, Satoshi Ota, Atsuo Kawahara

published 26 May 2015

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Damaging the Integrated HIV Proviral DNA with TALENs

Christy L. Strong, Horacio P. Guerra, Kiran R. Mathew, Nervik Roy, Lacy R. Simpson, Martin R. Schiller

published 06 May 2015

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CRISPR Diversity in E. coli Isolates from Australian Animals, Humans and Environmental Waters

Maxim S. Sheludchenko, Flavia Huygens, Helen Stratton, Megan Hargreaves

published 06 May 2015

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CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool

Manuel Stemmer, Thomas Thumberger, Maria del Sol Keyer, Joachim Wittbrodt, Juan L. Mateo

published 24 Apr 2015

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